Results 81 to 90 of about 35,846 (211)

Emerging DPP-4 inhibitors: focus on linagliptin for type 2 diabetes

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2013
Baptist GallwitzDepartment of Medicine IV, Eberhard-Karls-University Tübingen, Tübingen, GermanyAbstract: The first dipeptidyl-peptidase-IV (DPP-4) inhibitor for the treatment of type 2 diabetes became available in 2006. Since then, the
Gallwitz B
doaj  

Effectiveness and safety of dipeptidyl peptidase 4 inhibitors in the management of type 2 diabetes in older adults: a systematic review and development of recommendations to reduce inappropriate prescribing

open access: yesBMC Geriatrics, 2017
Background Preventable drug-related hospital admissions can be associated with drugs used in diabetes and the benefits of strict diabetes control may not outweigh the risks, especially in older populations.
Gisela Schott   +8 more
doaj   +1 more source

DPP-4 Inhibitors: The Seinfeld of Oral Antihyperglycemics

open access: yesThe Canadian Journal of Hospital Pharmacy, 2016
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Arden R, Barry, Ricky D, Turgeon
openaire   +3 more sources

Renal Effects of DPP-4 Inhibitors: A Focus on Microalbuminuria

open access: yesInternational Journal of Endocrinology, 2013
Incretin-based therapies represent one of the most promising options in type 2 diabetes treatment owing to their good effectiveness with low risk of hypoglycemia and no weight gain. Other numerous potential beneficial effects of incretin-based therapies
Martin Haluzík   +2 more
doaj   +1 more source

Advantages of incretin-based treatment in management of type 2 diabetes [PDF]

open access: yes, 2017
The risk of hypoglycemia with sulfonylureas is higher in the presence of diabetic nephropathy. Selective DPP-4 inhibitors lead to physiologic increases in the incretins GLP-1 and gastric inhibitory polypeptide and preferable for the management of ...
Abbas, Ahmad L.   +3 more
core  

Inappropriate Use of DPP-4 Inhibitors

open access: yes, 2014
Background: Dipeptidyl peptidase-4 (DPP-4) inhibitors are a newer class of oral anti-hyperglycemic agents for the treatment of type 2 diabetes. They have shown reduction of blood glucose, but potential impact on cardiovascular outcomes and long-term safety remain inconclusive. For that reasons DPP-4[for full text, please go to the a.m. URL]
Reichel, A   +4 more
openaire   +1 more source

DPP-4 inhibitor (sitagliptin)-induced seronegative rheumatoid arthritis

open access: yesBMJ Case Reports, 2019
Sitagliptin is a dipeptidyl peptidase-4 inhibitor commonly used in the treatment of type 2 diabetes mellitus for glycaemic control. Concerns have arisen regarding adverse events caused by this drug, particularly concerning arthralgias. Here, we report on a 56-year-old man being treated with sitagliptin who developed inflammatory arthritis after taking ...
Simonette, Padron   +3 more
openaire   +3 more sources

Alogliptin benzoate for management of type 2 diabetes

open access: yesVascular Health and Risk Management, 2015
Yoshifumi Saisho Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan Abstract: Dipeptidyl peptidase-4 (DPP-4) inhibitors, a new class of oral hypoglycemic agents, augment glucose-dependent insulin secretion and suppress ...
Saisho Y
doaj  

Clinical implementetion of vildagliptin: data from recent studies comparing incretin-based medications

open access: yesСахарный диабет, 2014
The introduction of DPP-4 inhibitors substantially increased therapeutic options for type 2 diabetes mellitus (T2DM). The unique mechanism of action allows using these agents both as monotherapy and in combination with conventional anti-diabetes drugs ...
Elena Valer'evna Biryukova
doaj   +1 more source

Renoprotective Effects of the Dipeptidyl Peptidase-4 Inhibitor Sitagliptin: A Review in Type 2 Diabetes [PDF]

open access: yes, 2017
Diabetic nephropathy (DN) is now the single commonest cause of end-stage renal disease (ESRD) worldwide and one of the main causes of death in diabetic patients.
Fernandes, Rosa   +3 more
core   +3 more sources

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