Results 81 to 90 of about 986,965 (260)

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

open access: yesFEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez   +4 more
wiley   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

open access: yesFEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada   +7 more
wiley   +1 more source

North Bridge at Youngstown Sheet and Tube Company's Campbell Works

open access: yes, 1910
This is a photograph of the North Bridge employee entrance at Youngstown Sheet and Tube's Campbell Works, East Youngstown (Campbell), Ohio, ca. 1910-1919. Shown is the gatehouse, gatekeeper, and the bridge that led into the plant. The sign posted above
Youngstown Sheet and Tube Company
core  

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

open access: yesFEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli   +2 more
wiley   +1 more source

Youngstown Sheet and Tube Company's Campbell Works

open access: yes, 1910
A view of the west end of Youngstown Sheet and Tube Company's Campbell Works, in East Youngstown (Campbell), Ohio, ca. 1910-1919. Named after James A. Campbell, the Campbell Works quickly became one of the Mahoning Valley's leaders in producing finished
Youngstown Sheet and Tube Company
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Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons   +33 more
wiley   +1 more source

Steady and unsteady CFD simulations of the Turbine-99 Draft Tube using CFX-5 and STREAM

open access: yes, 2005
The numerical prediction of the flow field in a hydraulic turbine draft tube is very challenging due to its complex flow properties and has already been studied in detail in two former ERCOFTAC Turbine-99 workshops.
Lundström, Staffan   +5 more
core   +2 more sources

Youngstown Sheet and Tube Company's Campbell Works boiler house

open access: yes, 1912
Refined waste gas is routed to the boiler house to be utilized as fuel to heat water for production of steam. After the boilers were installed, the building was constructed around them.
Youngstown Sheet and Tube Company
core  

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach   +23 more
wiley   +1 more source

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