Results 41 to 50 of about 18,389 (287)

Patient‐Reported Outcomes with Selpercatinib Among Patients with RET Fusion–Positive Non‐Small Cell Lung Cancer in the Phase I/II LIBRETTO‐001 Trial

open access: yesThe Oncologist, EarlyView., 2021
Abstract Background LIBRETTO‐001 is an ongoing, global, open‐label, phase I/II study of selpercatinib in patients with advanced or metastatic solid tumors. We report interim patient‐reported outcomes in patients with RET fusion–positive non‐small cell lung cancer (NSCLC).
Anna Minchom   +11 more
wiley   +1 more source

An updated list of Odonata of southwestern Bangladesh

open access: yesJournal of Threatened Taxa, 2018
An odonate survey was conducted throughout the southwestern region of Bangladesh, concentrating on eight districts and the Sundarban, from August 2014 to August 2016.
M. Sajjad Hossain Tuhin, M. Kawsar Khan
doaj   +1 more source

The impact of climate-induced distributional changes on the validity of biological water quality metrics [PDF]

open access: yes, 2010
We present data on the distributional changes within an order of macroinvertebrates used in biological water quality monitoring. The British Odonata (dragonflies and damselflies) have been shown to be expanding their range northwards and this could ...
Harvey, IF, Hassall, C, Thompson, DJ
core   +1 more source

Self‐Assembled Nanoclay Gel With Spheroid MSC‐Derived Exosome Mimetics to Integrate Demineralized Bone Matrix and Noggin‐Targeting miRNA for Synergistic Osteogenesis

open access: yesAdvanced Functional Materials, EarlyView.
We report a versatile nanoclay gel carrier platform that enhances the osteogenic efficacy of demineralized bone matrix (DBM) by integrating nanoclay‐based self‐assembly with cell‐derived exosome mimetics loaded with noggin‐targeting miR‐200c. This design amplifies BMP signaling, thereby promoting DBM‐mediated osteogenesis and offering a promising ...
Changlu Xu   +7 more
wiley   +1 more source

Patient‐Reported Outcomes with Selpercatinib Treatment Among Patients with RET‐Mutant Medullary Thyroid Cancer in the Phase I/II LIBRETTO‐001 Trial

open access: yesThe Oncologist, EarlyView., 2021
Abstract Background Medullary thyroid cancer (MTC) standard of care includes multikinase inhibitors (MKIs), which can exacerbate disease‐related diarrhea, primarily because of non‐RET kinase inhibition. We report diarrhea and other patient‐reported outcomes (PROs) with selpercatinib, a highly selective RET inhibitor, among patients with RET‐mutant MTC ...
Lori J. Wirth   +10 more
wiley   +1 more source

Carajathemis simone, new genus and species from Brazil (Odonata: Libellulidae)

open access: yesAnais da Academia Brasileira de Ciências, 2012
Carajathemis simone n. gen., n.sp. from the state of Pará, Brazil, is described and illustrated based on 22 specimens collected in a "canga" (laterite) lake within the forest at the Flona de Carajás, Parauapebas Municipality.
Angelo B.M. Machado
doaj   +1 more source

ETV2 Mediated Differentiation of Human Pluripotent Stem Cells Results in Functional Endothelial Cells for Engineering Advanced Vascularized Microphysiological Models

open access: yesAdvanced Healthcare Materials, EarlyView.
A robust method to generate functional human iPSC‐derived endothelial cells using inducible ETV2 expression. These cells self‐organize into stable, lumenized microvascular networks within microfluidic chips, surpassing conventional differentiation methods.
Shun Zhang   +12 more
wiley   +1 more source

Bottom‐Up Programming of Cell States in Cancer Organoids with Defined Synthetic Adhesion Cues

open access: yesAdvanced Materials, EarlyView.
A bottom‐up biomaterial platform is developed to program transcriptomic states in pancreatic cancer organoids by tuning adhesion cues within synthetic matrices. By combining a Design of Experiments framework with multiobjective optimization, matrix compositions are identified that enrich specific cellular programs like EMT.
Ali Nadernezhad   +6 more
wiley   +1 more source

Dragonflies

open access: yesRevista VIS: Revista do Programa de Pós-Graduação em Arte, 2017
O artigo apresenta uma série de trabalhos em artes visuais produzidos pelo autor ao longo de 15 anos que se concentram no estudo de libélulas e nas relações entre homens e animais. O processo criativo é compreendido aqui como investigação baseada em artes, por incorporar resultados imprevistos, desvios de percurso e desvelamentos inesperados sobre o ...
openaire   +3 more sources

Water quality: A hidden danger in anthropogenic desert catchments

open access: yesWildlife Society Bulletin, 2014
Natural rock pools, tinajas, and constructed catchments in the Sonoran Desert provide water for a wide variety of organisms. In 2012, we monitored water quality and amphibian and dragonfly use of wildlife waters in southwestern Arizona, USA.
Kerry L. Griffis‐Kyle   +2 more
doaj   +1 more source

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