Risk prediction of biliary infection after endoscopic drainage for malignant perihilar biliary obstruction: A 10-year multicenter retrospective study. [PDF]
Wang YF +10 more
europepmc +1 more source
Nanoparticle Immunoadjuvant Complexes Augment Germinal Center Responses to Vaccination
Scaffolding IL‐21 on the surface of a self‐assembling nanoparticle immunogen drives improved germinal center and humoral immune responses. These nanoparticle immunoadjuvant complexes (NICs) functionally modulate the germinal center driving improved somatic hypermutation and antibody maturation, suggesting this platform has potential utility as a ...
Nicholas J. Tursi +21 more
wiley +1 more source
Integrated analytical hierarchy process and neural network approaches for assessment of soil erosion risk in Manjira River sub-basin, India. [PDF]
Kumar S, Choudhary MK, Thomas T.
europepmc +1 more source
This study develops an mRNA therapy encoding a long‐acting GLP‐1/FGF21 fusion protein. A three‐tailed ionizable lipid engineered three‐component lipid nanoparticle delivers the mRNA to inguinal adipose tissue. In obese mice, this targeted, dual‐hormone treatment potently reduces body weight, fat mass, presenting a localized strategy for metabolic ...
Bin Ma +10 more
wiley +1 more source
Collaborative spatial decision making empowering urban flood governance toward city resilience. [PDF]
Radmehr A.
europepmc +1 more source
Atomic‐scale mechanisms governing multilevel resistive switching in HfOx‐based RRAM are reveal through advanced TEM. Thermally driven m‐phase rotation ([101]↔[011]) enables selective oxygen vacancy migration, which reconstructs atomic electric fields and dictates conduction—from Schottky/Poole‐Frenkel emission to Ohmic transport.
Wen Sun +9 more
wiley +1 more source
Building new hydrography and virtual watersheds to conserve freshwater fisheries. [PDF]
Benda L +4 more
europepmc +1 more source
A programmable nanoreactor was engineered for precise cGAS‐STING pathway activation in cancer immunotherapy. This strategy bridges targeted tumor DNA damage with DC immunomodulation, providing a translatable platform to unlock innate and adaptive antitumor immunity.
Shuang Liang +14 more
wiley +1 more source
Middle meningeal artery embolization with surgical evacuation improves outcomes in chronic subdural hematoma: a multi-institutional and multinational database study. [PDF]
Lakhani DA +4 more
europepmc +1 more source
Urban drainage models for flood forecasting: 1D/1D, 1D/2D and hybrid models [PDF]
Leitão, JP +5 more
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