Results 181 to 190 of about 242,983 (312)

Machine Learning Technology for EEG-Forecast of the Blood-Brain Barrier Leakage and the Activation of the Brain's Drainage System during Isoflurane Anesthesia. [PDF]

Biomolecules, 2023
Semyachkina-Glushkovskaya O, Sergeev K, Semenova N, Slepnev A, Karavaev A, Hramkov A, Prokhorov M, Borovkova E, Blokhina I, Fedosov I, Shirokov A, Dubrovsky A, Terskov A, Manzhaeva M, Krupnova V, Dmitrenko A, Zlatogorskaya D, Adushkina V, Evsukova A, Tuzhilkin M, Elizarova I, Ilyukov E, Myagkov D, Tuktarov D, Kurths J.   +24 more
europepmc   +1 more source

Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis

Advanced Science, EarlyView.
This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun, Qihong Li, Bixi Wang, Gang Wang, Ying Xue, Yibing Liang, Chenhe Hu, Zhenyu Wang, Xiaoge Gao, Haiheng Xu, Jun Song, Hailong Li, Liantao Li, Xiaoxiao Liu, Patrick Ming‐Kuen Tang, Qing Zhang   +15 more
wiley   +1 more source

The Outcome of the Use of an Improvised Chest Tube Drainage System in a Resource-Poor Centre. [PDF]

J West Afr Coll Surg
Mba EL, Guduf MI, Echieh CP, Wina FM, Mshelia NM, Udeh CC, Salihu I.   +6 more
europepmc   +1 more source

Use of a novel digital drainage system after pulmonary resection. [PDF]

J Thorac Dis, 2022
Geraci TC, Sorensen A, James L, Chen S, El Zaeedi M, Cerfolio RJ, Zervos M.   +6 more
europepmc   +1 more source

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source

A Novel Intra-Operative Irrigation-Drainage System for Robot-Assisted Thoracoscopic Esophagogastric Layered Anastomosis: Preliminary Practice and Short-Term Clinical Outcomes. [PDF]

Thorac Cancer
Zhong C, Li L, Wang Z, A-Lai GH, Zhao YS, Lin YD.   +5 more
europepmc   +1 more source

Choroidal Vortex Vein Drainage System in Central Serous Chorioretinopathy Using Ultra-Widefield Optical Coherence Tomography Angiography. [PDF]

Transl Vis Sci Technol, 2023
Luo Z, Xu Y, Xu K, Fan M, Tsui CK, Lu X, Wu B, Zhao X, Tang X, Wu P, Cui K, Yu S, Liang X.   +12 more
europepmc   +1 more source

Early Detection and Inhibition of Post‐Surgical Cancer Recurrence by Synthetic Extracellular Vesicles

Advanced Science, EarlyView.
An implantable hydrogel is designed to hold gene transfection agents engineered to turn early recurrent tumor cells into generators of synthetic EVs. These synthetic EVs can express engineered miR‐26a (E‐miR‐26a) for highly sensitive detection and PD‐1 (a PD‐L1‐blocking agent) for therapeutic intervention, thereby enabling early detection and ...
Junli Zhang, Wenjia Chang, Ruolin Hu, Peiyan Su, Qin Zhou, Yanan Li, Zhenzhong Zhang, Kaixiang Zhang   +7 more
wiley   +1 more source

Late Cenozoic river reorganization related to tectonic extrusion formed the modern drainage system in southeastern Tibet. [PDF]

Proc Natl Acad Sci U S A
Cao K, Wang G, Harrison TM, Yuan X, Leloup PH, Kusky TM, Cao L, Shen X, Cheng Y, Yao J, He X, Zhu Z, Xie S.   +12 more
europepmc   +1 more source

Anatomy, Physiology, and Disorders of the Spectacle, Subspectacular Space, and Its Lacrimal Drainage System in Squamates. [PDF]

Animals (Basel), 2023
Hellebuyck T, Solanes Vilanova F.
europepmc   +1 more source