Results 51 to 60 of about 33,548 (243)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The influence of chronotype on making music: Circadian fluctuations in pianists’ fine motor skills

Frontiers in Human Neuroscience, 2013
Making music on a professional level requires a maximum of sensorimotor precision. Chronotype-dependent fluctuations of sensorimotor precision in the course of the day may prove a challenge for musicians because public performances or recordings are ...
Floris Tijmen Van Vugt, Floris Tijmen Van Vugt, Katharina eTreutler, Eckart eAltenmüller, Hans-Christian eJabusch   +4 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Smart Forest Modeling Behavioral for a Greener Future: An AI Text-by-Voice Blockchain Approach with Citizen Involvement in Sustainable Forestry Functionality

FinTech
This paper introduces a novel approach to tree modeling architecture integrated with blockchain technology, aimed at enhancing landscape spatial planning and forest monitoring systems.
Dimitrios Varveris, Vasiliki Basdekidou, Chrysanthi Basdekidou, Panteleimon Xofis   +3 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Flexibility of movement organization in piano performance

Frontiers in Human Neuroscience, 2013
Piano performance involves a large repertoire of highly skilled movements. The acquisition of these exceptional skills despite innate neural and biomechanical constraints requires a sophisticated interaction between plasticity of the neural system and ...
Shinichi eFuruya, Eckart eAltenmüller
doaj   +1 more source

The Song of Macapat Semarangan: The Acculturation of Javanese and Islamic Culture

Harmonia: Journal of Arts Research and Education, 2020
The research objective is to explain the macapat Semarangan song which is the result of acculturation of Javanese and Islamic culture. The study used qualitative methods by uncovering the concept of processing of Javanese music and acculturation ...
Agus Cahyono, Widodo Widodo, Muhamad Jazuli, Onang Murtiyoso   +3 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Abdul Muluk Improvisation Techniques in the Warung Kajang Lako Program on TVRI Jambi

Mudra: Jurnal Seni Budaya
One of the characteristics of traditional Indonesian theater, including Abdul Muluk Jambi, is that the performances rely on the improvisational abilities of the actors.
Ikhsan Satria Irianto, Indra Gunawan, Lusi Handayani, Tofan Gustyawan   +3 more
doaj   +1 more source