Results 121 to 130 of about 2,577,009 (245)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
, 2014 This paper reports on the exciting Sydney study within the ground-breaking international rolling role project, which re-considered Heathcote’s rolling role strategy in a twenty-first century, web-based learning context.
Nicholls, Jennifer +2 more
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Dramatic Encounters Artistry, Community and Scholarship in Drama Teaching
, 2020 This book provides examples of outstanding quality drama teaching and community engagement. Each chapter describes and shares work that is characterized by artistry, with creativity and the aesthetic of the art form of drama as paramount.
Stinson, Madonna
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Constructivist inquiry and learning in drama
, 2007 Constructivism is an interpretive approach that emphasises the 'meaning making activity of the individual mind'. It is of particular relevance to drama education because learning in drama is based in process.
Wright, David
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'Drama as Therapy' research seminar
The RCSSD’s CDthAN (Central Dramatherapy Alumni Network) hosted a seminar celebration of over 1000 citations of the book - 'Drama as Therapy' (Routledge 1996, 2007) by Professor Phil Jones.
Jones, Phil, Coleman, Alyson
core +2 more sources
The Awakening: Makudlalwe. How play awakens the inner child in black Indigenous African adults
South African Journal of Arts TherapiesThe concept of the inner child represents the emotional and experiential core of individuals, often shaped by early life experiences. This article focuses on research which explored the significance of play in awakening this inner child in black ...
Nomfundo Ncanana
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source