Results 121 to 130 of about 1,849,126 (285)
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Representation of the female experience in Croatian short film
Filmski medij pruža uvid u vrijednosti društva u kojem nastaje te može poslužiti kao koristan uzorak za analizu različitih perspektiva i fenomena u tom kontekstu. Ovaj rad bavi se prikazom ženskog iskustva u hrvatskom kratkometražnom filmu.
Nežmah, Lana
core +1 more source
The Fabric of Traditional Theatre: Archived Memories and the Question of Cultural Ownership
Critical Stages, 2012 This paper is an attempt to offer a tentative theoretical framework for the discussion of the fabric of traditional theatre – what it is made of – and a possible approach that it will permit in our times.
Manabu Noda
doaj
FEBS Open Bio, EarlyView.Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
Referendums and political representation
The use of referendums is increasing globally, and as a result, the debate on whether they are a saviour or a danger to democracy has intensified. This chapter contributes to the discussion by examining the merits and challenges of referendums from a ...
Stadelmann-Steffen, Isabelle
core +1 more source
FEBS Open Bio, EarlyView.This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court +3 more
wiley +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
, 2011 The utility of tones spaces based on tone productions can be judged on the degree to which they (i) differentiate tone productions and (ii) predict tone perception. Here based on a production corpus, 5 different 2-dimensional tone spaces are constructed.
Attina, Virginie (R14534) +3 more
core
Representation, Interpretation, and Surrogative Reasoning [PDF]
, 2007 In this paper, I develop Mauricio Suárez’s distinction between denotation, epistemic representation, and faithful epistemic representation. I then outline an interpretational account of epistemic representation, according to which a vehicle represents a ...
Contessa, Gabriele
core
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source