Results 41 to 50 of about 10,779,080 (197)

Kidults, Mario Bros. and Pikachu: a brief study about the influence of Japanese pop culture on design

open access: yesProjetica, 2018
The present paper discusses the influences of Japanese pop culture on design production and consumption in Brazil, especially among young adults. We collected information on the history of cultural relationship between the two countries, as well as on ...
Michelle Cotrim   +2 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

PERAN MENGGAMBAR DALAM MEWUJUDKAN IDE KARYA ANIMASI

open access: yesNirmana, 2001
Animation had been known since 1940. Although obstructed by limited facilities and simple technologies%2C back then the Walt Disney had successfully produced animation masterpieces such as Pinocchio%2C Snow White%2C etc.
Heru Dwi Waluyanto
doaj  

The Illustration for children in Portugal in the first two decades of the 20th century

open access: yesProjetica, 2019
In Portugal, during the First Republic (1910-1926), politicians considered the education of the younger generation to be of major importance, since they would continue to support the revolutionary spirit.
Carla Maria Ramos
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

GAYA INDIES: GAYA DESAIN GRAFIS INDONESIA TEMPO DOELOE

open access: yesNirmana, 2005
Indies Graphic Design Style emerged in the Dutch Colonial Era%2C had reached the top artistically around 1930s. Indies Graphic Design Style developed by Dutch graphic designers%2C was a mixture between European modern design style of the early 20th ...
Bedjo Riyanto
doaj  

The iconography of playing cards

open access: yesProjetica, 2016
During the paper deals with the graphic-visual and symbolic features of the card game popularly known in Brazil as baralho and will investigate the material and immaterial aspects involving the setting of playing cards (materials, shapes, meanings and ...
Kamyla Lemes Soares
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

A interdisciplinaridade e o ensino do Design

open access: yesProjetica, 2011
Este artigo é um estudo teórico que buscou conceituar a interdisciplinaridade, o especialismo e o generalismo e caracterizar o Design como uma atividade interdisciplinar, cuja formação pro­fissional nas suas diversas modalidades (gráfico, moda, produto ...
Antonio Martiniano Fontoura
doaj   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

open access: yesMolecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani   +7 more
wiley   +1 more source

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