Results 51 to 60 of about 35,677 (234)
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers +7 more
wiley +1 more source
Project Review: ‘Making Room for Abolition’, by Lauren Williams
Diseña, 2023 This review positions Lauren Williams’ installation ‘Making Room for Abolition’, shown in ‘Monolith’ at Red Bull Arts in Detroit, as a speculative design project that presents a two-fold critique: one directed at US society and the other, at speculative
Aggie Toppins
doaj
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos +9 more
wiley +1 more source
The Trousers and Research Methodology for Oppressive Design
Diseña, 2023 As clothing represents social, political, and performative values pertaining to gender, it is not surprising that they also serve as oppressive designed objects.
Ory Bartal
doaj
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller +14 more
wiley +1 more source
Diseña, 2023 This contribution sheds light on discarded electronics repair in Accra, Ghana. After placing these practices in dialogue with the Western and Eurocentric narratives around the materiality of digital interactions and infrastructure, it delves into two ...
Cyrus Khalatbari
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma +16 more
wiley +1 more source
Book Overview. Repair: Sustainable Design Futures
Diseña, 2023 Repair, a humble act born of necessity, has become in the 21st century an expression of artistic and discursive resistance to humankind’s unmaking of our societies and our environment. As a concrete practice, it serves to bring us together, to re-engage
Kate Irvin , Markus Berger
doaj