Results 91 to 100 of about 3,105,687 (363)

Stimulation and Development of Intellectual Abilities in Preschool-Age Children

open access: yesEducation Sciences, 2020
The paper is focused on the investigation of impact of created experimental natural scientific programme for preschool-age children. Our programme concentrates on physics teaching adapted for preschool age in which children have possibilities to make ...
Ľubomíra Valovičová   +3 more
doaj   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

On Self-Approaching and Increasing-Chord Drawings of 3-Connected Planar Graphs [PDF]

open access: yesarXiv, 2014
An $st$-path in a drawing of a graph is self-approaching if during the traversal of the corresponding curve from $s$ to any point $t'$ on the curve the distance to $t'$ is non-increasing. A path has increasing chords if it is self-approaching in both directions.
arxiv  

Posing 3D Models from Drawing [PDF]

open access: yes, 2015
Inferring the 3D pose of a character from a drawing is a complex and under-constrained problem. Solving it may help automate various parts of an animation production pipeline such as pre-visualisation.
Gouvatsos, Alexandros   +3 more
core  

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Optimal Monotone Drawings of Trees [PDF]

open access: yesarXiv, 2016
A monotone drawing of a graph G is a straight-line drawing of G such that, for every pair of vertices u,w in G, there exists abpath P_{uw} in G that is monotone in some direction l_{uw}. (Namely, the order of the orthogonal projections of the vertices of P_{uw} on l_{uw} is the same as the order they appear in P_{uw}.) The problem of finding monotone
arxiv  

Small Superpatterns for Dominance Drawing

open access: yes, 2013
We exploit the connection between dominance drawings of directed acyclic graphs and permutations, in both directions, to provide improved bounds on the size of universal point sets for certain types of dominance drawing and on superpatterns for certain ...
Bannister, Michael J.   +2 more
core   +1 more source

Drawing Planar Graphs with Few Geometric Primitives [PDF]

open access: yes, 2017
We define the \emph{visual complexity} of a plane graph drawing to be the number of basic geometric objects needed to represent all its edges. In particular, one object may represent multiple edges (e.g., one needs only one line segment to draw a path ...
A Igamberdiev   +13 more
core   +4 more sources

Interplay of integrins and selectins in metastasis

open access: yesMolecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva   +2 more
wiley   +1 more source

Level-Planar Drawings with Few Slopes [PDF]

open access: yesarXiv, 2019
We introduce and study level-planar straight-line drawings with a fixed number $\lambda$ of slopes. For proper level graphs, we give an $O(n \log^2 n / \log \log n)$-time algorithm that either finds such a drawing or determines that no such drawing exists. Moreover, we consider the partial drawing extension problem, where we seek to extend an immutable
arxiv  

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