Results 71 to 80 of about 603,879 (267)

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

open access: yesFEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez   +4 more
wiley   +1 more source

Surfaceworks "Out There" In Here

open access: yesDrawing On, 2018
Black Contemporary is an experiential archive whereby ongoing investigations are conducted in an effort to expand knowledge specific to the study of atmospheric logics and the Midwestern agricultural landscape.
Peter Goché
doaj   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

open access: yesFEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court   +3 more
wiley   +1 more source

Technology and its impact on the expressive content in the pictorial works of the artist Alberto Burri

open access: yesJournal of Architecture, Art & Humanistic Science
echnique and its impact on the expressive content in the figurative works of the artist Alberto Puri It deals with artistic research and its impact on the expressive content in the figurative works of the artist Alberto Bori, where the war constituted a ...
Lecturer. hajar Al-Sayid Muhamad Al-Ghobari
doaj   +1 more source

Points of Departure

open access: yesDrawing On, 2015
This paper describes a project entitled Points of Departure, which forms part of a practice-led research investigation into how existing urban space might be both read and written using fiction, narrative and physical interventions.
Thomas Rivard
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Employing Ergonomic Standards in designing Educational Laboratory for Hand weaving

open access: yesالمجلة الدولية للعلوم الإنسانية والاجتماعية
Occupational safety is considered one of the fundamentals of the success of educational system, especially in light of the remarkable development in the Industrial Revolution and the change it brought in study patterns and educational strategies that ...
Dr. Hala Yousef Al-Osailan
doaj   +1 more source

The House of Multiple Dimensions

open access: yesDrawing On, 2015
This paper explores referencing as a creative practice in order to visually describe the role of references in the development of a design research project.
Ersi Ioannidou
doaj   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

open access: yesAging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho   +4 more
wiley   +1 more source

Introduction: On Drawing On

open access: yesDrawing On, 2015
Read online at: https://drawingon.org/Issue-01-IN ...
Chris French
doaj   +1 more source

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