Results 71 to 80 of about 3,499,858 (305)

Recognizing and Drawing IC-planar Graphs

open access: yes, 2015
IC-planar graphs are those graphs that admit a drawing where no two crossed edges share an end-vertex and each edge is crossed at most once. They are a proper subfamily of the 1-planar graphs.
C Auer   +27 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

A drawing book for digital eyes [PDF]

open access: yes, 2012
Looking at book covers may not tell you everything, but they do tell you something. A collection of leather-bound ‘how to draw’ books of the nineteen twenties exudes confidence, the expertise of the masters handed down.
Faure Walker, James
core  

Experimental Evaluation of Book Drawing Algorithms

open access: yes, 2017
A $k$-page book drawing of a graph $G=(V,E)$ consists of a linear ordering of its vertices along a spine and an assignment of each edge to one of the $k$ pages, which are half-planes bounded by the spine. In a book drawing, two edges cross if and only if
Klawitter, Jonathan   +2 more
core   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Redistricting: Drawing the Line

open access: yes, 2017
We develop methods to evaluate whether a political districting accurately represents the will of the people. To explore and showcase our ideas, we concentrate on the congressional districts for the U.S. House of representatives and use the state of North
Bangia, Sachet   +6 more
core   +1 more source

Compact Drawings of 1-Planar Graphs with Right-Angle Crossings and Few Bends

open access: yes, 2018
We study the following classes of beyond-planar graphs: 1-planar, IC-planar, and NIC-planar graphs. These are the graphs that admit a 1-planar, IC-planar, and NIC-planar drawing, respectively.
C Bachmaier   +13 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Employing Ergonomic Standards in designing Educational Laboratory for Hand weaving

open access: yesالمجلة الدولية للعلوم الإنسانية والاجتماعية
Occupational safety is considered one of the fundamentals of the success of educational system, especially in light of the remarkable development in the Industrial Revolution and the change it brought in study patterns and educational strategies that ...
Dr. Hala Yousef Al-Osailan
doaj   +1 more source

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