Results 61 to 70 of about 576,367 (247)

Hot and Wet

open access: yesDrawing On, 2019
The legacy of a temperate hegemony continues to influence how the tropical is perceived: largely as an exotic paradise or pestilence-ridden landscape. Architectural discourse has long deemed the equator a condition to be tempered; an atmospheric problem ...
Erik L'Heureux
doaj   +1 more source

Drawing Without Drawing

open access: yes, 2017
El modelado paramétrico integra tanto el diseño experimental (CAD) como su realización (CAM) y verificación (CAE). Es susceptible a las variaciones y mutaciones de los sistemas generativos, basados en parámetros que se traducen a un lenguaje de programación mediante algoritmos genéticos, como los denominó John Holland en 1970.
openaire   +3 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Introduction: Architecture Design Research

open access: yesDrawing On, 2019
Read online at: https://drawingon.org/Issue-03-IN ...
Dorian Wiszniewski, Chris French
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Technology and its impact on the expressive content in the pictorial works of the artist Alberto Burri

open access: yesJournal of Architecture, Art & Humanistic Science
echnique and its impact on the expressive content in the figurative works of the artist Alberto Puri It deals with artistic research and its impact on the expressive content in the figurative works of the artist Alberto Bori, where the war constituted a ...
Lecturer. hajar Al-Sayid Muhamad Al-Ghobari
doaj   +1 more source

Material Openings

open access: yesDrawing On, 2018
If an installation is charged with immersing an audience simultaneously in the alternative worlds to which it gestures, what role might the materiality of the installation play in the transposition of time and space implicit in such an immersion?
Michael Davis
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Surfaceworks "Out There" In Here

open access: yesDrawing On, 2018
Black Contemporary is an experiential archive whereby ongoing investigations are conducted in an effort to expand knowledge specific to the study of atmospheric logics and the Midwestern agricultural landscape.
Peter Goché
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

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