Results 111 to 120 of about 3,449,599 (284)
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Tag-Cloud Drawing: Algorithms for Cloud Visualization [PDF]
Tag clouds provide an aggregate of tag-usage statistics. They are typically sent as in-line HTML to browsers. However, display mechanisms suited for ordinary text are not ideal for tags, because font sizes may vary widely on a line.
Kaser, Owen, Lemire, Daniel
core +3 more sources
Invasive alien species pose significant ecological challenges, with Tradescantia fluminensis emerging as a major threat in Europe. This study investigates the potential of repurposing biomass from this invasive plant, collected in Galicia, for use in the
Antía Iglesias, Ángeles Cancela
doaj +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Very few experiments have been conducted on drawing wires of iron made from bog ore. One of them, however, was carried out at the forge at Lejre Land of Legends in Denmark. The iron used for the experiments was obtained from three different sites in Denmark where well-documented experiments in the extraction of bog iron ore took place.
openaire +2 more sources
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Drawing Students into Learning [PDF]
In addition to teaching the science of medicine, Professor Joanna Rowe shares the importance of positive energy and creates cartoons to help nursing students understand complex ...
Linfield Magazine Staff, Mileham, Mardi
core +1 more source
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Parametric modeling integrates both experimental design (CAD) and its realization (CAM) and verification (CAE). It is susceptible generative systems variations and ‘mutations’, based on parameters that are translated into a pro gramming language by ‘genetic algorithms’, as the named John Holland in 1970.
Agudo Martínez, María Josefa +2 more
openaire +1 more source

