Drugs for preventing red blood cell dehydration in people with sickle cell disease. [PDF]
BACKGROUND: Sickle cell disease is an inherited disorder of hemoglobin, resulting in abnormal red blood cells. These are rigid and may block blood vessels leading to acute painful crises and other complications.
Ballas, Samir K, Nagalla, Srikanth
core +2 more sources
Isolation and Characterisation of Quercitrin as a Potent Anti-Sickle Cell Anaemia Agent from Alchornea cordifolia [PDF]
Alchornea cordifolia Müll. Arg. (commonly known as Christmas Bush) has been used traditionally in Africa to treat sickle cell anaemia (a recessive disease, arising from the S haemoglobin (Hb) allele), but the active compounds are yet to be ...
Adeniyi, Olayemi +7 more
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The 4th Global Congress on Sickle Cell Disease Abstract Book 2022
HemaSphere, Volume 6, Issue S4, Page 1-64, August 2022.
wiley +1 more source
Antisickling activity of three species of Justicia from Kisangani (D.R. Congo): J. tenella,/i>, J. gendarussa and J. insularis [PDF]
Some medicinal plants have these last years, shown an antisickling activity. What indicates a new therapeutic way to the range of the poor African populations which are affected by this hemoglobinopathy.Justicia secunda is among these plants and it is ...
Mpiana, PT
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Management of the Sickle Cell Trait: An Opinion by Expert Panel Members [PDF]
: The number of individuals with the sickle cell trait exceeds 300 million worldwide, making sickle cell disease one of the most common monogenetic diseases globally.
De Franceschi L +12 more
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Comportamiento de las alteraciones renales en pacientes pediátricos con drepanocitosis [PDF]
Introduction: the drepanocytosis is a disease with multisystem impact. Renal disease begins in childhood and chronic consequences are glomerulopathy sickle glomerular with evolution to chronic renal failure.
Arango Inerarity, Dianevys +5 more
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Endocrine complications of haemochromatosis and heart failure mostly affect morbidity and mortality in polytransfused patients. This study analyzes endocrine dysfunctions and the impact of GH‐IGF‐1 axis alteration on cardiac performance in a population of 31 patients.
Michela Rosaria Campo +10 more
wiley +1 more source
Evaluation in vitro de l’activité antifalcémiante et effet antioxydant des extraits d’Uapaca heudelotii Baill. (Euphorbiaceae) [PDF]
En République Démocratique du Congo, comme dans de nombreux pays Africains, la drépanocytose ou anémie SS est l’une des causes majeures de morbidité et de mortalité et constitue un grave problème de Santé Publique.
Ekutsu, E +9 more
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Visualization of poikilocytosis as an emerging erythrocytic biomarker for fish health assessment
Poikilocytosis in fish encompasses various morphological changes in erythrocytes, including acanthocytes, echinocytes, spherocytes, dacrocytes, degmacytes, and more. This phenomenon results from both living and nonliving factors, such as pathological influences, environmental stress, anthropogenic impacts, and hereditary factors.
Avishek Bardhan +3 more
wiley +1 more source
Phytomedicines and Nutraceuticals: Alternative Therapeutics for Sickle Cell Anemia
Sickle cell anemia is a genetically inherited disease in which the “SS” individual possesses an abnormal beta globin gene. A single base substitution in the gene encoding the human β‐globin subunit results in replacement of β6 glutamic acid by valine, leading to the devastating clinical manifestations of sickle cell disease.
Ngozi Awa Imaga +4 more
wiley +1 more source

