Results 151 to 160 of about 1,262,540 (239)

Rare Case of Necrotizing Fasciitis With Polyarteritis Nodosa in a Multi‐Comorbid Patient

open access: yesClinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Necrotizing fasciitis can mimic cellulitis in immunocompromised patients, delaying diagnosis. This case highlights the importance of early clinical suspicion despite low LRINEC score. Prompt surgical intervention, appropriate antibiotics, and recognition of underlying conditions like polyarteritis nodosa are critical to reduce morbidity and ...
Syed Muhammed Salman Hassan   +5 more
wiley   +1 more source

DRESS Syndrome - Rare but Potentially Fatal Drug Reaction. [PDF]

open access: yesHawaii J Health Soc Welf
Fukuyama TH, Yamat BR, Tokeshi J.
europepmc   +1 more source

Adverse Reactions Identified after Approval of Novel Medicines: Analysis of 339 New Molecular Entities and Therapeutic Biologics

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 1120-1128, October 2026.
Postmarketing safety surveillance data identify safety issues not identified in preapproval clinical trials. We describe the frequency of new safety issues overall and by labeling section and the relationship of the most commonly added safety issues with the cumulative number of prescriptions dispensed via retail pharmacies.
Ellen Pinnow   +14 more
wiley   +1 more source

Extracellular Vesicles: Classification, Biological Functions, Diseases, and Therapeutic Opportunities

open access: yesMedComm, Volume 7, Issue 10, October 2026.
• EV content maintains cellular homeostasis and is involved in several disease onset and progression. • miRNA export in EVs depends on: RNA‐binding proteins recognizing motif sequences and on epitranscriptomic modifications. • The disclosure of delivery mechanisms is crucial for developing personalized EV‐based therapeutic tools. ABSTRACT Extracellular
Sabrina Garbo   +4 more
wiley   +1 more source

Vitamins and Chronic Wounds: How Altered Pharmacokinetics and Comorbidities Contribute to Vitamin Deficiencies

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 139, Issue 4, October 2026.
ABSTRACT Wound healing is complex and requires adequate amounts of macro‐ and micronutrients. When wound healing is delayed, a wound is considered chronic. Increasing evidence shows that vitamin deficiencies are prevalent in patients with chronic wounds, yet intervention studies with vitamin supplementation yielded inconsistent effects.
Michiel G. J. Balvers   +6 more
wiley   +1 more source

Characterization of Genetic and Chemical Drivers in the Pathogenesis of DRESS Syndrome: In Silico Study. [PDF]

open access: yesHealth Sci Rep
AbdElneam AI   +8 more
europepmc   +1 more source

Patch Testing in Paediatric Drug Hypersensitivity Reactions: Current Evidence and Clinical Implications

open access: yesContact Dermatitis, Volume 95, Issue 4, Page 349-357, October 2026.
ABSTRACT Drug hypersensitivity reactions (DHRs) are common in children and are diagnostically challenging, with cutaneous manifestations being the most common presentation. Patch testing (PT) is a well‐established tool for investigating delayed T‐cell‐mediated reactions and is widely used in patients with contact dermatitis.
Gabriele Simonetti   +7 more
wiley   +1 more source

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