Results 1 to 10 of about 3,260 (184)

Synthesis of Nano Hydroxyapatite: Application in Drug Delivery of Sulfasalazine [PDF]

open access: yesJournal of Nanostructures, 2015
In this work we synthesized Nano hydroxyapatite (HAp)  by Sol-gel method, Then we functionalized hydroxyapatite nanoparticle by use of  3-Aminopropyl trimethoxysilane (APTMS) , to improve the loading and control release of sulfasalazine drug bonded to ...
D. Moslemi   +2 more
doaj   +2 more sources

The effect of sulfasalazine in pentylenetetrazole-induced seizures in rats

open access: yesBrazilian Journal of Medical and Biological Research, 2021
We aimed to reveal the anti-convulsant effects sulfasalazine and its mechanism in pentylenetetrazole (PTZ)-induced seizures in rats. Forty-eight male Wistar albino rats (200-250 g) were randomly divided into two groups: 24 for electroencephalography (EEG)
E.S. Bora   +4 more
doaj   +2 more sources

Sulfasalazine-induced renal and hepatic injury in rats and the protective role of taurine [PDF]

open access: yesBioImpacts, 2016
Introduction: Sulfasalazine is a drug commonly administrated against inflammatory-based disorders. On the other hand, kidney and liver injury are serious adverse events accompanied by sulfasalazine administration.
Reza Heidari   +5 more
doaj   +2 more sources

Sulfasalazine prevents lung injury due to intra-abdominal sepsis in rats: possible role of Nrf2 and angiopoietin-2 [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 2023
This study aimed to investigate the effect of sulfasalazine in preventing and treating intra-abdominal sepsis-induced acute respiratory distress syndrome (ARDS) in a rat model. Forty male Wistar albino rats were used.
C. Dibekoğlu, Y. Uyanıkgil, O. Erbaş
doaj   +2 more sources

Sulfasalazine efficacy and tolerability in rheumatic diseases

open access: yesНаучно-практическая ревматология, 2005
Sulfasalazine is one of the main disease modifying drugs for the treatment of chronic inflammatory joint and spine diseases. The article describes mechanism of action of sulfasalazine and its main metabolites. Detailed information about anti-inflammatory
V. V. Badokin
doaj   +2 more sources

Development, characterization and evaluation of the dissolution profile of sulfasalazine suspensions [PDF]

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2015
This paper reports the development, characterization and in vitrodissolution behavior of sulfasalazine suspensions for treatment of chronic intestinal inflammatory diseases.
Mayre Aparecida Borges da Costa   +4 more
doaj   +3 more sources

Sulfasalazine Attenuates Staphylococcal Enterotoxin B-Induced Immune Responses

open access: yesToxins, 2015
Staphylococcal enterotoxin B (SEB) and related exotoxins are important virulence factors produced by Staphylococcus aureus as they cause human diseases such as food poisoning and toxic shock.
Teresa Krakauer
doaj   +2 more sources

Is it Crohn's disease? A severe systemic granulomatous reaction to sulfasalazine in patient with rheumatoid arthritis

open access: yesBMC Gastroenterology, 2001
Background Sulfasalazine is a widely used anti-inflammatory agent in the treatment of inflammatory bowel disease and several rheumatological disorders.
Haftel Hilary M   +3 more
doaj   +2 more sources

Sulfasalazine inhibits inflammation and fibrogenesis in pancreas via NF-κB signaling pathway in rats with oxidative stress-induced pancreatic injury

open access: yesDrug Design, Development and Therapy, 2016
Ya-Ru Wang,1,* Fei-Long Tian,2,* Ming-Xian Yan,1 Jin-Hua Fan,1 Li-Yun Wang,1 Rong-Guang Kuang,1 Yan-Qing Li3 1Department of Gastroenterology, Shandong Qianfoshan Hospital, Shandong University, 2Shandong University School of Medicine, 3Department of ...
Wang YR   +6 more
doaj   +1 more source

Effect of Garlic Oil on Sulfasalazine Induced Injury of Renal Tubules [PDF]

open access: yesThe Egyptian Journal of Histology, 2023
Introduction: Sulfasalazine is a disease modifying anti-rheumatic medication, used in the treatment of idiopathic arthritis. Kidney damage is one of its side effects.Objective: To investigate the protective role of garlic oil against sulfasalazine ...
fouad heikal   +4 more
doaj   +1 more source

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