Results 11 to 20 of about 3,260 (184)

How different is the status of depression and anxiety in patients with rheumatoid arthritis receiving methotrexate with sulfasalazine or hydroxychloroquine?

Russian Open Medical Journal, 2023
Background — Depression and anxiety are among the most common clinical manifestations in patients with rheumatoid arthritis (RA). Sulfasalazine and hydroxychloroquine are important medications used to treat these patients.
Mansour Babaei, Mehdi Dorparvar, Behnaz Yousef Ghahari, Behzad Heidari, Hemmat Gholinia, Sussan Moudi   +5 more
doaj   +1 more source

Effect of sulfasalazine on endothelium-dependent vascular response by the activation of Nrf2 signalling pathway

Frontiers in Pharmacology, 2022
Background: Diabetes mellitus leads to endothelial dysfunction and accumulation of oxygen radicals. Sulfasalazine-induced Nrf2 activation reduces oxidative stress in vessels.
Muhammed Ikbal Sonmez, Muhammed Ikbal Sonmez, Muhammed Ikbal Sonmez, Andleeb Shahzadi, Cagla Kose, Cagla Kose, Haktan Sonmez, Sibel Ozyazgan, Ahmet Gokhan Akkan, Ahmet Gokhan Akkan   +9 more
doaj   +1 more source

Sulfasalazine induces mitochondrial dysfunction and renal injury

Renal Failure, 2017
Sulfasalazine is a commonly used drug for the treatment of rheumatoid arthritis and inflammatory bowel disease. There are several cases of renal injury encompass sulfasalazine administration in humans.
Hossein Niknahad, Reza Heidari, Roya Mohammadzadeh, Mohammad Mehdi Ommati, Forouzan Khodaei, Negar Azarpira, Narges Abdoli, Mahdi Zarei, Behnam Asadi, Maryam Rasti, Babak Shirazi Yeganeh, Vahid Taheri, Arastoo Saeedi, Asma Najibi   +13 more
doaj   +1 more source

Cross-reactivity in drug hypersensitivity reactions to sulfasalazine and sulfamethoxazole [PDF]

, 2010
Sulfonamides are generally classified into 2 groups: antibiotics and non-antibiotics. Recent studies showed that patients allergic to sulfonamide antibiotics do not have a specific risk for an allergy to sulfonamide non-antibiotic.
Beeler, A., Pichler, W. J., Zawodniak, A., Lochmatter, P.   +3 more
core   +1 more source

Case report: Sulfasalazine-induced hypersensitivity [PDF]

, 2023
Drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic symptoms (DRESS) is a systemic inflammatory condition that is characterized by multisystemic involvement (liver, blood, and skin), heterogeneous manifestations ...
Mikhail M. Kostik, Ekaterina M. Kuchinskaya, Irina A. Chikova   +2 more
core   +1 more source

Interaction of sulfasalazine with outer surface of boron-nitride nanotube as a drug carrier in aqueous solution: insights from quantum mechanics and Monte Carlo simulation

BMC Chemistry, 2023
The improvement of the solubility of sulfasalazine in physiological media was the major aim of this study. Accordingly, BNNT inspected as a notable candidate for the carriage of this drug in aqueous media.
Sepideh Ketabi, Saba Shalmashi, Sara Hallajian   +2 more
doaj   +1 more source

Sulfasalazine reduces placental secretion of antiangiogenic factors, up-regulates the secretion of placental growth factor and rescues endothelial dysfunctionResearch in context

EBioMedicine, 2019
Background: Preeclampsia is a major complication of pregnancy with no medical treatment. It is associated with placental oxidative stress, hypoxia and inflammation leading to soluble fms-like tyrosine kinase 1 (sFlt-1) and soluble endoglin (sENG ...
Fiona C. Brownfoot, Natalie J. Hannan, Ping Cannon, Vi Nguyen, Roxanne Hastie, Laura J. Parry, Sevvandi Senadheera, Laura Tuohey, Stephen Tong, Tu'uhevaha J. Kaitu'u-Lino   +9 more
doaj   +1 more source

The clinical characteristics, putative drugs, and optimal management of 62 patients with stevens-johnson syndrome and/or toxic epidermal necrolysis: A retrospective observational study

Indian Dermatology Online Journal, 2022
Background: Case reviews of severe cutaneous adverse drug reactions (ADRs) such as SJS/TEN provide useful insights for clinical characteristics, putative drugs, and management protocols.
Sujaya Manvi, Vikram K Mahajan, Karaninder S Mehta, Pushpinder S Chauhan, Sanket Vashist, Ravinder Singh, Prabal Kumar   +6 more
doaj   +1 more source

UniPR1331: Small Eph/Ephrin Antagonist Beneficial in Intestinal Inflammation by Interfering with Type-B Signaling

Pharmaceuticals, 2021
Eph receptors, comprising A and B classes, interact with cell-bound ephrins generating bidirectional signaling. Although mainly related to carcinogenesis and organogenesis, the role of Eph/ephrin system in inflammation is growingly acknowledged. Recently,
Carmine Giorgio, Marika Allodi, Simone Palese, Andrea Grandi, Massimiliano Tognolini, Riccardo Castelli, Alessio Lodola, Lisa Flammini, Anna Maria Cantoni, Elisabetta Barocelli, Simona Bertoni   +10 more
doaj   +1 more source

Influence of Different Diets on the Degradation of Sulfasalazine by Colon Bacteria Determined Using MimiCol³

Pharmaceuticals, 2023
The microbiome of the colon is characterized by its great diversity. This varies not only intra- but also interindividually and is influenced by endogenous and exogenous factors, such as dietary and lifestyle factors.
Dariah-Sohreh Seradj, Regine Beeck, Annika Haase, Julius Krause, Philipp Schick, Werner Weitschies   +5 more
doaj   +1 more source