Results 11 to 20 of about 26,729 (245)

Synthesis of Nano Hydroxyapatite: Application in Drug Delivery of Sulfasalazine [PDF]

Journal of Nanostructures, 2015
In this work we synthesized Nano hydroxyapatite (HAp)  by Sol-gel method, Then we functionalized hydroxyapatite nanoparticle by use of  3-Aminopropyl trimethoxysilane (APTMS) , to improve the loading and control release of sulfasalazine drug bonded to ...
D. Moslemi, S. Mortazavi-Derazkola, S. Masoumeh Ghoreishi   +2 more
doaj   +3 more sources

The effect of sulfasalazine in pentylenetetrazole-induced seizures in rats

Brazilian Journal of Medical and Biological Research, 2021
We aimed to reveal the anti-convulsant effects sulfasalazine and its mechanism in pentylenetetrazole (PTZ)-induced seizures in rats. Forty-eight male Wistar albino rats (200-250 g) were randomly divided into two groups: 24 for electroencephalography (EEG)
E.S. Bora, R. Karaali, P.Y. Akyol, G. Yurtsever, O. Erbaş   +4 more
doaj   +2 more sources

Sulfasalazine-induced renal and hepatic injury in rats and the protective role of taurine [PDF]

BioImpacts, 2016
Introduction: Sulfasalazine is a drug commonly administrated against inflammatory-based disorders. On the other hand, kidney and liver injury are serious adverse events accompanied by sulfasalazine administration.
Reza Heidari, Maryam Rasti, Babak Shirazi Yeganeh, Hossein Niknahad, Arastoo Saeedi, Asma Najibi   +5 more
doaj   +2 more sources

Sulfasalazine efficacy and tolerability in rheumatic diseases

Научно-практическая ревматология, 2005
Sulfasalazine is one of the main disease modifying drugs for the treatment of chronic inflammatory joint and spine diseases. The article describes mechanism of action of sulfasalazine and its main metabolites. Detailed information about anti-inflammatory
V. V. Badokin
doaj   +2 more sources

Effect of sulfasalazine on endothelium-dependent vascular response by the activation of Nrf2 signalling pathway

Frontiers in Pharmacology, 2022
Background: Diabetes mellitus leads to endothelial dysfunction and accumulation of oxygen radicals. Sulfasalazine-induced Nrf2 activation reduces oxidative stress in vessels.
Muhammed Ikbal Sonmez, Muhammed Ikbal Sonmez, Muhammed Ikbal Sonmez, Andleeb Shahzadi, Cagla Kose, Cagla Kose, Haktan Sonmez, Sibel Ozyazgan, Ahmet Gokhan Akkan, Ahmet Gokhan Akkan   +9 more
doaj   +2 more sources

Development, characterization and evaluation of the dissolution profile of sulfasalazine suspensions [PDF]

Brazilian Journal of Pharmaceutical Sciences, 2015
This paper reports the development, characterization and in vitrodissolution behavior of sulfasalazine suspensions for treatment of chronic intestinal inflammatory diseases.
Mayre Aparecida Borges da Costa, Ana Lucia Vazquez Villa, Rita de Cássia da Silva Ascenção Barros, Eduardo Ricci-Júnior, Elisabete Pereira dos Santos   +4 more
doaj   +3 more sources

Sulfasalazine Attenuates Staphylococcal Enterotoxin B-Induced Immune Responses

Toxins, 2015
Staphylococcal enterotoxin B (SEB) and related exotoxins are important virulence factors produced by Staphylococcus aureus as they cause human diseases such as food poisoning and toxic shock.
Teresa Krakauer
doaj   +2 more sources

Sulfasalazine inhibits inflammation and fibrogenesis in pancreas via NF-κB signaling pathway in rats with oxidative stress-induced pancreatic injury

Drug Design, Development and Therapy, 2016
Ya-Ru Wang,1,* Fei-Long Tian,2,* Ming-Xian Yan,1 Jin-Hua Fan,1 Li-Yun Wang,1 Rong-Guang Kuang,1 Yan-Qing Li3 1Department of Gastroenterology, Shandong Qianfoshan Hospital, Shandong University, 2Shandong University School of Medicine, 3Department of ...
Wang YR, Tian FL, Yan MX, Fan JH, Wang LY, Kuang RG, Li YQ   +6 more
doaj   +1 more source

Sulfasalazine induced seizures and dysphasia

, 1994
We describe the case of a 46-year-old woman with rheumatoid arthritis who developed a severe reaction to sulfasalazine, characterized by dysphasia, seizures, rash and the development of strongly positive pANCA (perinuclear antineutrophil cytoplasmic ...
Gordon, C, Heath, D A, Situnayake, R D, Hill, M E   +3 more
core   +6 more sources

Neuroprotective effects of sulfasalazine in experimental model of seizures and epilepsy. [PDF]

BMC Neurosci
Bojja SL, Hari G, Bandyopadhyay I, Kolathur KK, Chamallamudi MR.   +4 more
europepmc   +2 more sources