Results 11 to 20 of about 12,850 (181)

Sulfasalazine reduces placental secretion of antiangiogenic factors, up-regulates the secretion of placental growth factor and rescues endothelial dysfunctionResearch in context

EBioMedicine, 2019
Background: Preeclampsia is a major complication of pregnancy with no medical treatment. It is associated with placental oxidative stress, hypoxia and inflammation leading to soluble fms-like tyrosine kinase 1 (sFlt-1) and soluble endoglin (sENG ...
Fiona C. Brownfoot, Natalie J. Hannan, Ping Cannon, Vi Nguyen, Roxanne Hastie, Laura J. Parry, Sevvandi Senadheera, Laura Tuohey, Stephen Tong, Tu'uhevaha J. Kaitu'u-Lino   +9 more
doaj   +1 more source

Herbal therapy for treating rheumatoid arthritis (review) [PDF]

, 2011
Background Herbal medicine interventions have been identified as having potential benefit in the treatment of rheumatoid arthritis (RA). Objectives To update an existing systematic (Cochrane) review of herbal therapies in RA. Search methods
Cameron, Melainie, Chrubasik, Sigrun, Gagnier, Joel J.   +2 more
core   +1 more source

The clinical characteristics, putative drugs, and optimal management of 62 patients with stevens-johnson syndrome and/or toxic epidermal necrolysis: A retrospective observational study

Indian Dermatology Online Journal, 2022
Background: Case reviews of severe cutaneous adverse drug reactions (ADRs) such as SJS/TEN provide useful insights for clinical characteristics, putative drugs, and management protocols.
Sujaya Manvi, Vikram K Mahajan, Karaninder S Mehta, Pushpinder S Chauhan, Sanket Vashist, Ravinder Singh, Prabal Kumar   +6 more
doaj   +1 more source

Restoring Conjunctival Tolerance by Topical Nuclear Factor–κB Inhibitors Reduces Preservative-Facilitated Allergic Conjunctivitis in Mice [PDF]

, 2014
Purpose.: To evaluate the role of nuclear factor–κB (NF-κB) activation in eye drop preservative toxicity and the effect of topical NF-κB inhibitors on preservative-facilitated allergic conjunctivitis.
Gabelloni, María Laura, Galletti, Jeremías Gastón, Giordano, Mirta Nilda, Guzman, Mauricio, Sabbione, Florencia, Trevani, Analía Silvina, Vanzulli, Silvia   +6 more
core   +1 more source

Sulfasalazine efficacy and tolerability in rheumatic diseases

Научно-практическая ревматология, 2005
Sulfasalazine is one of the main disease modifying drugs for the treatment of chronic inflammatory joint and spine diseases. The article describes mechanism of action of sulfasalazine and its main metabolites. Detailed information about anti-inflammatory
V. V. Badokin
doaj   +1 more source

UniPR1331: Small Eph/Ephrin Antagonist Beneficial in Intestinal Inflammation by Interfering with Type-B Signaling

Pharmaceuticals, 2021
Eph receptors, comprising A and B classes, interact with cell-bound ephrins generating bidirectional signaling. Although mainly related to carcinogenesis and organogenesis, the role of Eph/ephrin system in inflammation is growingly acknowledged. Recently,
Carmine Giorgio, Marika Allodi, Simone Palese, Andrea Grandi, Massimiliano Tognolini, Riccardo Castelli, Alessio Lodola, Lisa Flammini, Anna Maria Cantoni, Elisabetta Barocelli, Simona Bertoni   +10 more
doaj   +1 more source

Is it Crohn's disease? A severe systemic granulomatous reaction to sulfasalazine in patient with rheumatoid arthritis

BMC Gastroenterology, 2001
Background Sulfasalazine is a widely used anti-inflammatory agent in the treatment of inflammatory bowel disease and several rheumatological disorders.
Haftel Hilary M, Greenson Joel, Quallich Leonard G, Fontana Robert J   +3 more
doaj   +1 more source

Influence of Different Diets on the Degradation of Sulfasalazine by Colon Bacteria Determined Using MimiCol³

Pharmaceuticals, 2023
The microbiome of the colon is characterized by its great diversity. This varies not only intra- but also interindividually and is influenced by endogenous and exogenous factors, such as dietary and lifestyle factors.
Dariah-Sohreh Seradj, Regine Beeck, Annika Haase, Julius Krause, Philipp Schick, Werner Weitschies   +5 more
doaj   +1 more source

Influence of peptidylarginine deiminase type 4 genotype and shared epitope on clinical characteristics and autoantibody profile of rheumatoid arthritis. [PDF]

, 2009
Background: Recent evidence suggests that distinction of subsets of rheumatoid arthritis (RA) depending on anticyclic citrullinated peptide antibody (anti-CCP) status may be helpful in distinguishing distinct aetiopathologies and in predicting the ...
Burmester, G.R., Dörner, T., Egerer, K., Gruber, R., Hoppe, B., Häupl, T., Kiesewetter, H., Salama, A.   +7 more
core   +1 more source

Establishment of a new canine inflammatory mammary carcinoma cell line and analysis of its cystine-glutamate transporter subunit expression

Journal of Veterinary Research, 2022
Inflammatory mammary carcinoma (IMC) is a rare disease with a poor prognosis and one affecting dogs. Inflammatory breast carcinoma (IBC) is a subtype of malignant breast cancer in humans with a high degree of malignancy and a similarly poor prognosis ...
Itoh Harumichi, Naruse Ryo, Tani Kenji, Sunahara Hiroshi, Nemoto Yuki, Nakaichi Munekazu, Iseri Toshie, Horikirizono Hiro, Itamoto Kazuhito   +8 more
doaj   +1 more source