Results 31 to 40 of about 3,260 (184)

Sulfasalazine for the treatment of preeclampsia in a nitric oxide synthase antagonist mouse model

, 2023
INTRODUCTION: Development of a therapeutic that targets the pathophysiological elements of preeclampsia would be a major advance for obstetrics, with potential to save the lives of countless mothers and babies.
Kaitu'u-Lino, TJ, Kadife, E, Brownfoot, FC, Beard, S, Harper, A, de Alwis, N, Hannan, NJ, Binder, NK   +7 more
core   +1 more source

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐Modifying Antirheumatic Drug

Arthritis Care &Research, EarlyView.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie, Timothy Beukelman, Nicholas P. McCormick, Jeffrey R. Curtis   +3 more
wiley   +1 more source

Influence of therapy with methotrexate, sulfasalazine and glucocorticoids on disease activity and erosions progression in patients with early rheumatoid arthritis

Научно-практическая ревматология, 2007
Objective. To perform a comparative assessment of methotrexate and sulfasalazine efficacy when administered as monotherapy and in combination with low doses of GC in early RA considering disease activity and erosions development in joints of hands and ...
G Togizbaev, D E Karateev
doaj   +1 more source

EFFECT OF DSS ADMINISTRATION AND SULFASALAZINE TREATMENT ON BODY WEIGHT AND OXIDATIVE STRESS IN EXPERIMENTAL ULCERATIVE COLITIS IN MICE [PDF]

Al-Azhar Journal of Pharmaceutical Sciences, 2017
Ulcerative colitis (UC) is a type of inflammatory bowel disease (IBD), characterized by chronic inflammation of the gastrointestinal tract. In general, IBD is more common in Western than in Eastern places, and in industrialized than in developing ...
Samar Gerges
doaj   +1 more source

A Case Report of Intratesticular Hematoma in a Patient with Reiter’s Syndrome

Diagnostics, 2023
We present a case of a 28-year-old male patient with a spontaneous intratesticular hematoma. He had no history of trauma but experienced sudden onset of painful swelling in his right testis. Initially, testicular malignancy was suspected.
Jia-Jyun Jhang, Szu-Ju Chen, Chi-Ping Huang, Huey-Yi Chen, Wei-Ching Lin, Yung-Hsiang Chen, Wen-Chi Chen   +6 more
doaj   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Rheumatoid nodules in the lung parenchyma in rheumatoid arthritis

Научно-практическая ревматология, 2019
Rheumatoid nodules (RNs) are one of the most common extra-articular manifestations of rheumatoid arthritis (RA), but are rarely located in lung tissue. The development of extra-articular (systemic) manifestations of RA is associated with the high levels ...
A. M. Satybaldyev, L. P. Ananyeva
doaj   +1 more source

Associations of Rheumatoid Arthritis Disease Activity With Frailty Over Five Years of Follow‐up

Arthritis Care &Research, EarlyView.
Objective To evaluate whether rheumatoid arthritis (RA) disease activity is associated with frailty both in cross‐section and longitudinally. Methods Participants within the Veterans Affairs Rheumatoid Arthritis (VARA) registry enrolled from 2003 to 2022 were included.
Courtney N. Loecker, Yangyuna Yang, Punyasha Roul, Aaron Baraff, Myra S. Schmaderer, Lani Zimmerman, Kaleb Michaud, Namrata Singh, Grant W. Cannon, Gary Kunkel, Ted R. Mikuls, Ariela R. Orkaby, Joshua F. Baker, Bryant R. England, Katherine D. Wysham   +14 more
wiley   +1 more source

Safety assessment of sulfasalazine: a pharmacovigilance study based on FAERS database

Frontiers in Pharmacology
BackgroundSulfasalazine is a widely used anti-inflammatory medication for treating autoimmune disorders such as ulcerative colitis (UC), Crohn’s disease, and rheumatoid arthritis.
Wangyu Ye, Yuan Ding, Meng Li, Zhihua Tian, Shaoli Wang, Zhen Liu   +5 more
doaj   +1 more source

Mycobacterium tuberculosis-Induced Upregulation of the COX-2/mPGES-1 Pathway in Human Macrophages Is Abrogated by Sulfasalazine

Frontiers in Immunology, 2022
Macrophages are the primary human host cells of intracellular Mycobacterium tuberculosis (M.tb) infection, where the magnitude of inflammatory reactions is crucial for determining the outcome of infection. Previously, we showed that the anti-inflammatory
Wenfei Wang, Wenfei Wang, Yuping Ning, Yuping Ning, Yejun Wang, Guofang Deng, Simona Pace, Stefanie A. Barth, Christian Menge, Kehong Zhang, Kehong Zhang, Youchao Dai, Yi Cai, Xinchun Chen, Oliver Werz   +14 more
doaj   +1 more source