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Poking Pluripotency: Nanoinjection Into Human iPSCs. [PDF]

open access: yesAdv Mater
Nanoinjection into hiPSCs: silicon nanotubes effectively transfect human induced pluripotent stem cells (hiPSCs) with mRNA, enabled by a delayed extracellular matrix application and enhanced surface functionalization. Nanoinjection is demonstrated with several reporter mRNA, including co‐transfection of mCherry and GFP.
Harberts J   +5 more
europepmc   +2 more sources

Is switching to T-DM1 still justified in HER2-negative residual breast cancer after neoadjuvant systemic therapy? [PDF]

open access: yesBreast
The standard of care for HER2-positive and hormone receptor-positive breast cancer patients who receive neoadjuvant chemotherapy (NACT) combined with trastuzumab, with or without pertuzumab, is to continue with adjuvant T-DM1 in cases of an incomplete ...
Wiebren Tjalma   +3 more
doaj   +2 more sources

Comprehensive Genomic Profiling and Therapeutic Implications for Patients with Advanced Cancers: The Experience of an Academic Hospital

open access: yesDiagnostics, 2023
Next-generation sequencing (NGS) can be used to detect tumor-specific genomic alterations. This retrospective single-center study aims to assess the application of an extensive NGS panel to identify actionable alterations and initiate matched targeted ...
Laure-Anne Teuwen   +4 more
doaj   +1 more source

Increasing pulse pressure ex vivo, mimicking acute physical exercise, induces smooth muscle cell-mediated de-stiffening of murine aortic segments

open access: yesCommunications Biology, 2023
The mechanisms by which physical activity affects cardiovascular function and physiology are complex and multifactorial. In the present study, cardiac output during rest or acute physical activity was simulated in isolated aortic segments of healthy ...
Cédric H. G. Neutel   +5 more
doaj   +1 more source

Obstructive Sleep Disorders in Down Syndrome’s Children with and without Lower Airway Anomalies

open access: yesChildren, 2021
(1) Background: Obstructive sleep apnea (OSA) and lower airway anomalies are both highly prevalent in children with Down syndrome (DS). However, little is known on the interaction between both.
Mariska De Lausnay   +3 more
doaj   +1 more source

Integrated Analgesic Care in the Current Human Monkeypox Outbreak: Perspectives on an Integrated and Holistic Approach Combining Old Allies with Innovative Technologies

open access: yesMedicina, 2022
Monkeypox (MPX) is a zoonotic infection caused by an orthopoxvirus that is endemic to Central and Western Africa. The MPX virus is a part of the same family of viruses as the variola virus, which causes smallpox.
Guy Henri Hans   +2 more
doaj   +1 more source

Drie portretten

open access: yesThe Rijksmuseum Bulletin, 1957
R. van Luttervelt
doaj   +2 more sources

Blinded by the Light: Artificial Light Lowers Mate Attraction Success in Female Glow-Worms (Lampyris noctiluca L.)

open access: yesInsects, 2021
Nocturnal light pollution from anthropogenic origin is increasing worldwide and is recognised as a major threat for nocturnal biodiversity. We studied the impact of artificial light on the mate attraction success of female common glow-worms (Lampyris ...
Mira Van den Broeck   +3 more
doaj   +1 more source

High Pulsatile Load Decreases Arterial Stiffness: An ex vivo Study

open access: yesFrontiers in Physiology, 2021
Measuring arterial stiffness has recently gained a lot of interest because it is a strong predictor for cardiovascular events and all-cause mortality.
Cédric H. G. Neutel   +5 more
doaj   +1 more source

The influenza vaccine for nursing and care professionals at emergency services in Flanders

open access: yesHuman Vaccines & Immunotherapeutics, 2021
Background: The Belgian Superior Health Council recommends seasonal influenza vaccination for people working in the health care sector in order to reduce the risk of the influenza virus being transmitted to people at risk.
Matthijs Samyn   +3 more
doaj   +1 more source

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