Genome-wide scans using archived neonatal dried blood spot samples [PDF]
Background Identification of disease susceptible genes requires access to DNA from numerous well-characterised subjects. Archived residual dried blood spot samples from national newborn screening programs may provide DNA from entire populations and ...
Wiuf Carsten +11 more
doaj +2 more sources
Patterned Dried Blood Spot Cards for Improved Sampling of Whole Blood [PDF]
Dried blood spot (DBS) cards perform many functions for sampling blood that is intended for subsequent laboratory analysis, which include: (i) obviating the need for a phlebotomist by using fingersticks, (ii) enhancing the stability of analytes at ...
Jessica C., Brooks +3 more
core +2 more sources
Hematocrit-independent sampling enables white blood cell counts from patterned dried blood spot cards [PDF]
The accurate and efficient measurement of white blood cell (WBC) counts is vital for monitoring general patient health and can aid in diagnosing a range of possible infections or diseases.
Charles R., Mace +3 more
core +2 more sources
A hepatitis C avidity test for determining recent and past infections in both plasma and dried blood spots [PDF]
DBS testing has been used successfully to detect HCV antibody positive individuals. Determining how long someone has been infected is important for surveillance initiatives. Antibody avidity is a method that can be used to calculate recency of infection.
Hutchinson, Sharon +7 more
core +4 more sources
Detection of HIV-1 infection in dried blood spots from a 12-year-old ABO bedside test card [PDF]
Background and Objectives: We tested dried blood from an ABO bedside test card which had been stored at room temperature for 12 years, to prove that a patient with HIV-1 infection had been infected by blood transfusion. Materials and Methods: Immunoblots
Mayer, G. +9 more
core +1 more source
Nontargeted Mass Spectrometry of Dried Blood Spots for Interrogation of the Human Circulating Metabolome [PDF]
Advances in high resolution, nontargeted mass spectrometry allow for the simultaneous measure of thousands of metabolites in a single biosample. Application of these analytical approaches to population-scale human studies has been limited by the need for
Eowyn, Acres +9 more
core +1 more source
Pharmacokinetic study of praziquantel enantiomers and its main metabolite R-trans-4-OH-PZQ in plasma, blood and dried blood spots in Opisthorchis viverrini-infected patients [PDF]
Praziquantel (PZQ) is the treatment of choice for infections with the liver fluke Opisthorchis viverrini, a major health problem in Southeast Asia. However, pharmacokinetic (PK) studies investigating the disposition of PZQ enantiomers (R- and S-PZQ) and ...
Jennifer Keiser +15 more
core +2 more sources
Introduction: Screening for vertically transmitted infection is mandatory and must be conducted at the first prenatal consultation. The most vulnerable women's groups are those at the lowest socio-economic level.
Ney Boa-Sorte +5 more
doaj +1 more source
BackgroundAccurate routine HIV viral load testing is essential for assessing the efficacy of antiretroviral treatment (ART) regimens and the emergence of drug resistance.
Lara Vojnov +18 more
doaj +1 more source
Multi-mycotoxin analysis using dried blood spots and dried serum spots [PDF]
In this study, a rapid multi-mycotoxin approach was developed for biomonitoring and quantification of 27 important mycotoxins and mycotoxin metabolites in human blood samples. HPLC-MS/MS detection was used for the analysis of dried serum spots (DSS) and dried blood spots (DBS).
Osteresch, Bernd +3 more
openaire +3 more sources

