Results 241 to 250 of about 2,829,518 (302)

The Suitability of Dried Blood Spot Sampling for Pharmacokinetic Studies in Veterinary Medicine. [PDF]

Vet Sci
Bardhi A, Barbarossa A, Joubert A, Gehring R, Lambertini C, Romagnoli N.   +5 more
europepmc   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

Establishing the performance and acceptability of dried blood spot sampling to screen for islet-specific autoantibodies. [PDF]

Diabet Med
Faustini SE, Quinn LM, Hoque M, Young S, Bentley C, Kwok HF, Plant T, Litchfield I, Boardman F, Greenfield SM, Narendran P, Richter AG.   +11 more
europepmc   +1 more source

KLF5 Downregulation Links Impaired BNIP3‐Mediated Mitophagy to Inflammatory Valve Remodeling in Calcific Aortic Valve Disease

Advanced Science, EarlyView.
In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian, Jia‐Xi Gu, Zhang Yue, Chun‐Ze Yuan, Hai‐Bin Ji, Ao Li, Yu Zhong, Xiu‐Fan Xu, Yu‐Qiu He, Ye‐Fan Jiang, Hong‐Shan Chen, Xiang Chen, Meng‐Lin Chao, Yong‐Feng Shao   +13 more
wiley   +1 more source

SickleInAfrica Consortium: A Seven-Country Study Evaluating the Performance of Dried Blood Spot Point-of-Care Testing in Newborn Screening for Sickle Cell Disease. [PDF]

Hemoglobin
Nnodu OE, Mupfururirwa W, Kiguli S, Chirande L, Toure BA, Sarfo FS, Kuona P, Guindo A, Louden A, Nguweneza A, Balandya E, Chunda-Liyoka C, Nembaware V, Oosterwyk C, Jonas M, Morrice J, Kengne AP, Nkya S, Masamu U, Makani J, Moru PO, Koya A, Martin H, Chikara L, Amuzu EX, Kaweme NM, Nakibirango M, Okeke C, Nwegbu M, Oppong-Mensah Y, Munube D, Chianumba RI, Madu A, Namazzi R, Kandawasvika G, Mahenge N, Mmbando B, Jonathan A, Mgaya J, Manongi J, Minja I, Peprah E, Wonkam A.   +42 more
europepmc   +1 more source

Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape

Advanced Science, EarlyView.
Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim, Minju Lee, Yiming Wang, Eunjin Choi, Ji Sun Park, Kyungmin Park, Hayoung Jeon, Donghyun Kim, Donghyun Lee, Yeeun Lee, Kee‐Pyo Kim, Eunha Kim, Heebeom Koo   +12 more
wiley   +1 more source

Performance of Dried Blood Spot Cards for Serologic Detection of HPV16 Antibodies in Oropharyngeal Squamous Cell Carcinoma Patients. [PDF]

Microorganisms
Rahman MM, Bose S, Chen L, Burris JL, Aouad R, Arnold SM, Yeoh M, Michels B, Waterboer T, Lang Kuhs KA.   +9 more
europepmc   +1 more source

Revisiting Thyroglobulin Measurement: Current Methods and Future Perspectives Using Dried Blood Spot Sampling for Enhanced Clinical Practice. [PDF]

Metabolites
Monza N, Fumagalli C, Pagani L, Porto NS, Di Nicoli F, Chinello C, Serrao S, Bossi E, Nobile M, Pagni F, Magni F, Denti V.   +11 more
europepmc   +1 more source

Dried Blood Spot Analysis for Simultaneous Quantification of Antiepileptic Drugs Using Liquid Chromatography-Tandem Mass Spectrometry. [PDF]

Rapid Commun Mass Spectrom
Abady MM, Jeong JS, Kwon HJ.
europepmc   +1 more source