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What Is Next For Dried Blood Spots?
Bioanalysis, 2012In the last several years, dried blood spot (DBS) sampling has re-emerged and attracted a great interest in the pharmaceutical industry as a microsampling technology for drug discovery and development studies. Although significant progress has been made to understand strengths and weaknesses of the technique, many organizations are still at the ...
Qin C, Ji +4 more
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Quantification of insulin in dried blood spots
Journal of Laboratory and Clinical Medicine, 1998A method has been developed in which the concentrations of insulin in dried blood spots on filter paper can be estimated. The technique involves elution of blood from the paper, evaporation, and rehydration in assay buffer. The resuspended samples are then assayed by radioimmunoassay.
B, Dowlati +4 more
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Radioimmunoassay of Thyroxine in Dried Blood Spots
Journal of Paediatrics and Child Health, 1978Sadler, W. A., Lynskey, Clare P., and Legge, M. (1978). Aust. Paediatr. J., 14, 154–182. Radioimmunoassay of thyroxine in dried blood spots. A rapid precise radioimmunoassay for thyroxine (T4) in dried blood spots on filter paper has been developed, and appears entirely suitable for use as a mass screening procedure for the early diagnosis of neonatal ...
W A, Sadler, C P, Lynskey, M, Legge
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Measuring thiamine status in dried blood spots
Clinica Chimica Acta, 2020A reliable and robust method with minimum sample collection requirement for thiamine assay is needed in clinical and research settings.A simple and robust assay for three vitamers (thiamine, Th; thiamine monophosphate, TMP; and thiamine diphosphate, TDP) using a 6.35-mm dried blood spot (DBS) disc was developed, validated and applied.We were able to ...
Yichao Huang +2 more
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Current Pharmaceutical Design, 2011
Tuberculosis (TB) is a high-burden infectious disease, especially in low and middle-income countries. The efforts to eliminate this disease are challenged by the emergence of multidrug resistance and TB-HIV coinfection. The cumulative knowledge on pharmacokinetics/pharmacodynamics of antituberculosis agents has recently encouraged therapeutic drug ...
Vu, D.H. +4 more
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Tuberculosis (TB) is a high-burden infectious disease, especially in low and middle-income countries. The efforts to eliminate this disease are challenged by the emergence of multidrug resistance and TB-HIV coinfection. The cumulative knowledge on pharmacokinetics/pharmacodynamics of antituberculosis agents has recently encouraged therapeutic drug ...
Vu, D.H. +4 more
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Measurement of leptin in dried blood spot samples
American Journal of Human Biology, 2006Leptin is important in a wide range of physiological processes, but logistical constraints associated with venipuncture blood collection have limited research on leptin in diverse, community-based settings. The aim of this short report is to present and validate an enzyme immunoassay method for quantifying leptin in samples of capillary whole blood ...
Aaron A, Miller +2 more
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Quantification of valproic acid in dried blood spots
Scandinavian Journal of Clinical and Laboratory Investigation, 2014Therapeutic drug monitoring (TDM) of the antiepileptic drug valproic acid (VPA) is recommended in patients with multiple drug therapy or with concomitant disabilities to ensure treatment efficacy and avoid adverse reactions in both adults and children. The use of sampling techniques compatible with home sampling, such as dried blood spot sampling could
Anton, Pohanka +4 more
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Evaluation of CMV DNA in dried blood spot.
The new microbiologica, 2020Cytomegalovirus is the primary viral cause of congenital infection. However, diagnosis may be difficult for clinical and technical reasons. Currently, evaluation of CMV DNA on dried blood spot (DBS) is an important instrument to define a congenital infection.
Bottino, Paolo +6 more
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Dried Blood Spot (Dbs) methodology study for biomarker discovery in Dried Blood Spot (lsd).
2021Lysosomal storage diseases (LSDs) are a heterogeneous group of inherited metabolic diseases caused by mutations in genes encoding for proteins involved in the lysosomal degradation of macromolecules. They occur in approximately 1 in 5000 live births and pose a lifelong risk.
Rus, C.M. +4 more
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MEASURING THEOPHYLLINE ON DRIED BLOOD SPOTS
The Lancet, 1984G F, Batstone, E J, Coombes, T R, Gamlen
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