Results 101 to 110 of about 2,696,364 (300)

Human iPSC‐Derived Tissue‐Engineered Nigrostriatal Pathway for Chronic Restoration of Dopaminergic Axon Tracts in a Rat Parkinson's Model

Advanced Healthcare Materials, EarlyView.
Inspired by conventional cell therapy and emerging bioengineering approaches, the tissue‐engineered nigrostriatal pathway (TE‐NSP) has an anatomically‐inspired design comprising a population of human dopaminergic neurons with unidirectional, long‐projecting axon tracts.
Wisberty J. Gordián‐Vélez, Dimple Chouhan, Kevin D. Browne, James Lim, Saarang P. Karandikar, Rodrigo A. España, John E. Duda, H. Isaac Chen, D. Kacy Cullen   +8 more
wiley   +1 more source

The use of DNA from archival dried blood spots with the Infinium HumanMethylation450 array [PDF]

, 2013
Background: Dried blood (Guthrie card) spots provide an efficient way to collect and store blood specimens. DNA from this source has been utilised for a number of molecular analyses including genome-wide association studies, but only few studies have ...
Giles, Graham G., Wong, EM, Helen Tsimiklis, Tsimiklis, H, Laura Baglietto, Wong, Ee Ming, BAGLIETTO, LAURA, Southey, MC, John L Hopper, Hopper, John L., Joo, JiHoon E., English, Dallas R., Ee Ming Wong, Severi, G, Hopper, JL, Wong, NC, Giles, GG, JiHoon E Joo, Daniel J Park, Wong, Nicholas C., Dallas R English, Tsimiklis, Helen, Park, DJ, Melissa C Southey, Jung, Chol Hee, Severi, Gianluca, English, DR, Chol-Hee Jung, Park, Daniel J., Baglietto, L, Gianluca Severi, Nicholas C Wong, Southey, Melissa C., Jung, CH, Joo, JHE, Graham G Giles   +35 more
core   +1 more source

Dried Blood Spots May Improve Detection of Blood Doping [PDF]

Clinical Chemistry, 2019
In 2019, investigations have found at least 40 blood bags, 5 cross-country skiers, 5 cyclists, and 1 physician involved in a highly sophisticated blood doping scandal (1). The findings highlight the need for improved detection of blood doping practices.
openaire   +2 more sources

Engineering Antigen Density on M13 Bacteriophage for Personalized Nanovaccine

Advanced Healthcare Materials, EarlyView.
Increasing antigen density on the phage capsid impacts phage uptake and antigen cross‐presentation by antigen‐presenting cells, leading to enhanced activation of antitumor CD8+ T cells in the draining lymph nodes. These activated CD8+ T cells subsequently recognize the antigen‐expressing tumors and mediate their specific cytotoxic killing, thereby ...
Shengnan Huang, Allison Madow, Jack Rudrum, Huaiyao Peng, Hao Nghi Luu, Peiyan Dong, Jifa Qi, Angela M. Belcher   +7 more
wiley   +1 more source

MOESM1 of Detection of malaria parasites in dried human blood spots using mid-infrared spectroscopy and logistic regression analysis

, 2019
Additional file 1. Detection of five Plasmodium species from dried blood spots (DBS) by nested PCR ...
Klaas Wynne (1348641), Johnson Swai (7472087), Fredros Okumu (4633318), Elihaika Minja (7472081), Said Abbasi (7472090), Salum Mapua (6085358), Halfan Ngowo (5828951), Simon Babayan (7472099), Marta Maia (5544446), Mario JimĂŠnez (7472102), Doreen Siria (7472093), Francesco Baldini (255533), Heather Ferguson (273353), Caleb Stica (7472096), Maggy Sikulu-Lord (6085361), Emmanuel Mrimi (7472084), Ally Olotu (108545), Emmanuel Mwanga (7317866), Prashanth Selvaraj (5677121)   +18 more
core   +1 more source

Anti‐Inflammatory and Neuroactive Effects of Polymer‐Coated Iron Oxide Nanoparticles Functionalized With Interleukin 4 for Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
Polymer‐coated IONPs functionalized with IL‐4 display respective neuroactive and anti‐inflammatory actions on neural progenitor cells and macrophages/microglia in vitro. When examined chronically in a rat experimental model of spinal cord injury, rGO scaffolds carrying these nanosystems adequately integrate into the lesion, significantly reduce ...
Julia Martínez‐Ramírez, Paloma Lozano‐Picazo, María de Lamo‐Atencia, Andrea Ferreras, Esther Benayas‐Martín, Elena Fernández‐López, Marina Sánchez‐Petidier, Verónica Barranco‐Maresca, Víctor Caz, Anne des Rieux, Juliana M. Rosa, María del Puerto Morales, María C. Serrano   +12 more
wiley   +1 more source

HBV DNA levels in Dried Blood Spots (DBS) after 2, 6 and 12 weeks of storage at room temperature.

, 2016
HBV DNA levels in Dried Blood Spots (DBS) after 2, 6 and 12 weeks of storage at room temperature.
Hailemichael Desalegn (3335361), Kathrine Stene-Johansen (3335370), Nadeem Yaqoob (3335364), Joakim Overbo (3335373), Hanna Aberra (3335367), Asgeir Johannessen (46209), Nega Berhe (385244)   +6 more
core   +1 more source

Assessment of Dried Blood Spots for DNA Methylation Profiling

Wellcome Open Research, 2019
Abstract Background DNA methylation reflect health-related environmental exposures and genetic risk, providing insights into aetiological mechanisms and potentially predicting disease onset, progression and treatment response.
Rosie M. Walker, Louise MacGillivray, Sarah McCafferty, Nicola Wrobel, Lee Murphy, Shona M. Kerr, Stewart W. Morris, Archie Campbell, Andrew M. McIntosh, David J. Porteous, Kathryn L. Evans   +10 more
openaire   +3 more sources

Topically Delivered Treg‐Attracting Microparticle‐Hydrogel Composites Recruit Regulatory T Cells and Limit Cardiac Injury After Severe Ischemia

Advanced Healthcare Materials, EarlyView.
CCL22‐releasing PLGA microparticles (MP) suspended in topically applied hydrogels (HEART) establish a sustained chemokine gradient at the injured myocardium. HEART recruits CCR4+ regulatory T cells, reduces infarct size and graft fibrosis, and improves cardiac function.
Matthew A. Borrelli, Alexis T. Reese, Jordan J. P. Warunek, Betsy Ann Varghese, Canxing Lin, Jeffery J. Baust, Brenda McMahon, Steven R. Little, Hēth R. Turnquist   +8 more
wiley   +1 more source

Publisher Correction: Genetic correlates of vitamin D-binding protein and 25-hydroxyvitamin D in neonatal dried blood spots [PDF]

Correction to "Genetic correlates of vitamin D-binding protein and 25-hydroxyvitamin D in neonatal dried blood ...
Skogstrand, Kristin, Hougaard, David M., Cohen, Arieh S., Borbye-Lorenzen, Nis, Plana-Ripoll, Oleguer, Albiñana, Clara, Wray, Naomi R., Petersen, Liselotte V., Børglum, Anders D., Nordentoft, Merete, Boelt, Sanne Grundvad, Revez, Joana A., Mortensen, Preben Bo, Zhu, Zhihong, Musliner, Katherine L., Agerbo, Esben, McGrath, John J., Werge, Thomas, Vilhjálmsson, Bjarni J., Bulik, Cynthia M., Privé, Florian   +20 more
core   +1 more source