Quantitation of 5-Methyltetrahydrofolic Acid in Dried Blood Spots and Dried Plasma Spots by Stable Isotope Dilution Assays. [PDF]
PLoS ONE, 2015 Because of minimal data available on folate analysis in dried matrix spots (DMSs), we combined the advantages of stable isotope dilution assays followed by LC-MS/MS analysis with DMS sampling to develop a reliable method for the quantitation of plasma 5 ...
Markus Kopp, Michael Rychlik
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A UHPLC–MS/MS Method for Therapeutic Drug Monitoring of Aciclovir and Ganciclovir in Plasma and Dried Plasma Spots [PDF]
Biomedicines, 2021 The role of therapeutic drug monitoring (TDM) of valaciclovir (VA)/aciclovir (A) and valganciclovir/ganciclovir (VG/G) in critically ill patients is still a matter of debate.
Federica Pigliasco +8 more
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Differences of Phenylalanine Concentrations in Dried Blood Spots and in Plasma: Erythrocytes as a Neglected Component for This Observation [PDF]
Metabolites, 2021 Monitoring phenylalanine (Phe) concentrations is critical for the management of phenylketonuria (PKU). This can be done in dried blood spots (DBS) or in EDTA plasma derived from capillary or venous blood. Different techniques are used to measure Phe, the
Dorothea Haas +9 more
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IP-10 can be measured in dried plasma spots in patients with chronic hepatitis C infection. [PDF]
PLoS ONE, 2012 The chemokine IP-10 (CXCL10) is a candidate marker for hepatitis C virus (HCV) fibrosis monitoring. The aim of this proof-of-concept study is to assess if IP-10 measurements from dried plasma spots (DPS) are accurate in HCV-infected patients with either ...
Morten Ruhwald +4 more
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Quantification of Zonisamide in Dried Blood Spots and Dried Plasma Spots by UPLC–MS/MS: Application to Clinical Practice [PDF]
Molecules, 2022 In this research, a UHPLC–MS/MS method was developed and validated for the determination of zonisamide in dried plasma spots (DPS) and dried blood spots (DBS).
Milena Rmandić +5 more
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Increasing the sensitivity of Simoa via bead count reduction facilitates the quantification of pTau‐181 in dried plasma spots [PDF]
Alzheimer’s & Dementia: Translational Research & Clinical InterventionsIntroduction The exclusion of affected populations from Alzheimer's disease (AD) clinical research limits our understanding of disease heterogeneity and its impact on clinical care.
Pablo Mohaupt +3 more
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The Imprinted PARAFILM as a New Carrier Material for Dried Plasma Spots (DPSs) Utilizing Desorption Electrospray Ionization Mass Spectrometry (DESI-MS) in Phospholipidomics [PDF]
Frontiers in Chemistry, 2021 The application of desorption electrospray ionization mass spectrometry (DESI-MS) and dried blood spot (DBS) sampling has been successfully implemented several times.
Jiansong Chen +8 more
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Evaluation of the performance of Abbott m2000 and Roche COBAS Ampliprep/COBAS Taqman assays for HIV-1 viral load determination using dried blood spots and dried plasma spots in Kenya. [PDF]
PLoS ONE, 2017 BackgroundRoutine HIV viral load testing is not widely accessible in most resource-limited settings, including Kenya. To increase access to viral load testing, alternative sample types like dried blood spots (DBS), which overcome the logistic barriers ...
Clement Zeh +7 more
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Analysis of purines and pyrimidines across biospecimens: influence of storage temperature and duration [PDF]
Scientific ReportsPurines and pyrimidines are key cellular components for the development, proliferation, and repair of cells and tissues, whose circulating levels are associated with various diseases.
Rachel Wurth +9 more
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PCR-based detection of cytomegalovirus in neonates and children, with emphasis on congenital and neonatal-screening cohorts: A systematic review and meta-analysis [PDF]
SAGE Open MedicineBackground Cytomegalovirus (CMV) is one of the commoner infections of childhood and the leading non-genetic cause of sensorineural hearing loss. Diagnosis in children is not straightforward.
Manal Abdel Haleem A. Abusalah +8 more
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