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Matrix effects influence biochemical signatures and metabolite quantification in dried blood spots

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Cremer J   +6 more
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Dried Blood Spots in Doping Analysis

Bioanalysis, 2021
A series of dried blood spot (DBS) detection methods for doping agents have been developed in the last two decades. The DBS technique minimizes invasiveness and reduces storage and shipping costs. Recently, the World Anti-Doping Agency announced the use of DBS for the 2022 Beijing Winter Olympic Games and Paralympic Games owing to the advantages of the
Yuling Yuan, Youxuan Xu, Jianghai Lu
openaire   +2 more sources

Stabilized dried blood spot collection

Analytical Biochemistry, 2016
During the collection phase of the dried blood spot method, practitioners need to ensure that there is no smearing of the blood sample on the filter paper or else readings from it will be invalid. This can be difficult to accomplish in the field if there is relative motion between the site of blood discharge on the finger and the filter paper.
Darren, McMorran   +5 more
openaire   +2 more sources

What Is Next For Dried Blood Spots?

Bioanalysis, 2012
In the last several years, dried blood spot (DBS) sampling has re-emerged and attracted a great interest in the pharmaceutical industry as a microsampling technology for drug discovery and development studies. Although significant progress has been made to understand strengths and weaknesses of the technique, many organizations are still at the ...
Qin C, Ji   +4 more
openaire   +2 more sources

Glutathione peroxidase in dried blood spots

Experientia, 1978
A new procedure utilizing dried blood spots was developed for detecting glutathione peroxidase deficiency. Samples from a known patient with a partial defect and from rats with an induced deficiency were distinguished from respective control groups by their longer defluorescence endpoints.
S, Kelly, L, Schedlbauer
openaire   +2 more sources

Quantification of insulin in dried blood spots

Journal of Laboratory and Clinical Medicine, 1998
A method has been developed in which the concentrations of insulin in dried blood spots on filter paper can be estimated. The technique involves elution of blood from the paper, evaporation, and rehydration in assay buffer. The resuspended samples are then assayed by radioimmunoassay.
B, Dowlati   +4 more
openaire   +2 more sources

Radioimmunoassay of Thyroxine in Dried Blood Spots

Journal of Paediatrics and Child Health, 1978
Sadler, W. A., Lynskey, Clare P., and Legge, M. (1978). Aust. Paediatr. J., 14, 154–182. Radioimmunoassay of thyroxine in dried blood spots. A rapid precise radioimmunoassay for thyroxine (T4) in dried blood spots on filter paper has been developed, and appears entirely suitable for use as a mass screening procedure for the early diagnosis of neonatal ...
W A, Sadler, C P, Lynskey, M, Legge
openaire   +2 more sources

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