Results 41 to 50 of about 2,696,364 (300)
Blood and dried blood spot telomere length measurement by qPCR: assay considerations. [PDF]
PLoS ONE, 2013 Measurement of telomere length is crucial for the study of telomere maintenance and its role in molecular pathophysiology of diseases and in aging. Several methods are used to measure telomere length, the choice of which usually depends on the type and ...
DeAnna L Zanet +5 more
doaj +1 more source
Analytical Validation of Familial Hypercholesterolemia Biomarkers in Dried Blood Spots
International Journal of Neonatal Screening, 2022 Heterozygous familial hypercholesterolemia (HeFH) is a common, treatable genetic disorder characterized by premature atherosclerosis and cardiovascular disease, yet the majority of affected individuals remain undiagnosed.
Patrice K. Held +5 more
doaj +1 more source
Feasibility of detecting snake envenomation biomarkers from dried blood spots
Analytical Science Advances, 2023 Biofluid proteomics is a sensitive and high throughput technique that provides vast amounts of molecular data for biomarker discovery. More recently, dried blood spots (DBS) have gained traction as a stable, noninvasive, and relatively cheap source of ...
Cara F. Smith +8 more
doaj +1 more source
Analysis of Lyso-Globotriaosylsphingosine in Dried Blood Spots [PDF]
Annals of Laboratory Medicine, 2013 Recently, lyso-globotriaosylsphingosine (lyso-Gb3) was found to be elevated in plasma of treatment naive male patients and some female patients with Fabry Disease (FD). This study tested whether lyso-Gb3 could be analyzed in dried blood spots (DBS) from filter cards and whether concentrations are elevated in newborn infants with FD.
Johnson, Britt +9 more
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Dried Blood Spot Test Estimation of Urea [PDF]
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1985 The analysis of urea in serum and whole blood samples dried onto filter paper has been investigated. In both cases the sample volume is not critical nor is the volume of sample applied to the filter paper if sample discs of consistent dimensions can be punched from the dried paper.
R M, Plumbe, H G, Worth
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Cross-Sectional Study of Soil-Transmitted Helminthiases in Black Belt Region of Alabama, USA
Emerging Infectious Diseases, 2023 We conducted a cross-sectional study to determine the prevalence of soil-transmitted helminthiases (STH) in areas of rural Alabama, USA, that have sanitation deficits.
Claudette Poole +8 more
doaj +1 more source
Dried blood spot analysis; facing new challenges
Journal of Applied Bioanalysis, 2015 Over the last decade, DBS analysis has gained popularity for TDM because it’s a patient friendly sampling proce- dure [1-4]. Additional advantages are prolonged sample stability, lower risk of infections and transportation at ambient temperature [1-3,5].
Koster, Remco A +2 more
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The use of freeze-dried blood samples affects the results of a dried blood spot analysis
Clinical Biochemistry, 2022 Dried blood spot (DBS) microsampling has several advantages over venous blood sampling. In a clinical validation study of tacrolimus microsampling it was noted that tacrolimus DBS concentrations ([Tac]DBS) were systematically higher than tacrolimus whole-blood concentrations ([Tac]WB).
Francke, Marith I. +4 more
openaire +2 more sources
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source