Results 81 to 90 of about 1,204,666 (274)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Objetivou-se com este trabalho avaliar os efeitos da deriva simulada, pela aplicação de doses reduzidas de glyphosate em diferentes cultivares e estádios de desenvolvimento do algodoeiro. O ensaio foi realizado a campo em Alta Floresta, MT.
O.M. Yamashita, S.C. Guimarães
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Machine Learning Methods for Evaluation of Technical Factors of Spraying in Permanent Plantations
Considering the demand for the optimization of the technical factors of spraying for a greater area coverage and minimal drift, field tests were carried out to determine the interaction between the area coverage, number of droplets per cm2, droplet ...
Vjekoslav Tadić +2 more
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Interpreting Image Patterns for Agricultural Sprays Using Statistics and Machine Learning Techniques
The atomization of liquid spray solutions through nozzles is a mechanism for delivering many pesticides to the target. The smallest drop sizes (
Steven Cryer, John Raymond
doaj +1 more source
Design and Test of a New Inductive Force Sensor
The currently accepted interval of weekly cast changes in the treatment of clubfeet seems unsubstantiated. A force sensor is needed to determine the adaptation rate of a clubfoot to establish what cast change interval would be most effective and ...
Robert Bram Giesberts +2 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Spiral wave drift in an electric field and scroll wave instabilities
I present the numerical computation of speed and direction of the drift of a spiral wave in an excitable medium in the presence of an electric field. In contrast to earlier results, the drift speed presents a strong variation close to the parameter value
A. T. Winfree, D. Barkley, Hervé Henry
core +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source

