Results 111 to 120 of about 930,869 (362)

Evidence for a mid-Pleistocene change of ice-drift pattern in the Nordic seas [PDF]

open access: yes, 2003
Sediment proxy records from a continuous, 1.5 million year long deep-sea sediment core from a site in the western Norwegian Sea were used to obtain new insights into the nature of palaeoceanographic change in the northern North Atlantic (Nordic seas ...
Bauch   +53 more
core   +2 more sources

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

Open-source feature-tracking algorithm for sea ice drift retrieval from Sentinel-1 SAR imagery

open access: yes, 2016
. A computationally efficient, open-source feature-tracking algorithm, called ORB, is adopted and tuned for sea ice drift retrieval from Sentinel-1 SAR (Synthetic Aperture Radar) images.
S. Muckenhuber, A. Korosov, S. Sandven
semanticscholar   +1 more source

Sediments in Arctic sea ice: Implications for entrainment, transport and release [PDF]

open access: yes, 1994
Despite the Arctic sea ice cover's recognized sensitivity to environmental change, the role of sediment inclusions in lowering ice albedo and affecting ice ablation is poorly understood.
Dethleff, Dirk   +7 more
core   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

open access: yesFEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang   +9 more
wiley   +1 more source

Simulations with the sea ice model CICE documenting the impact of improved sea ice physics [PDF]

open access: yes, 2018
Sea ice thickness data (CryoSat-2) have been used to identify and correct shortcomings in simulating winter ice growth in the widely used sea ice model CICE.
Schroeder, David
core   +1 more source

Analytical investigation of ice floe drift in the marginal ice zone [PDF]

open access: yesWIT Transactions on Engineering Sciences, 2008
Analytical solutions were constructed to investigate the ice floe drift, velocity field, and trajectories. The mathematical model considers the balance of atmosphere and ocean drag forces on ice floe, including skin and body drag forces from wind, waves, and currents.
M. Rahman   +2 more
openaire   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei   +7 more
wiley   +1 more source

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

open access: yesFEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji   +3 more
wiley   +1 more source

Open-source sea ice drift algorithm for Sentinel-1 SAR imagery using a combination of feature tracking and pattern matching

open access: yes, 2016
. An open-source sea ice drift algorithm for Sentinel-1 SAR imagery is introduced based on the combination of feature tracking and pattern matching.
S. Muckenhuber, S. Sandven
semanticscholar   +1 more source

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