Results 81 to 90 of about 930,869 (362)

Dynamics and Thermodynamics of the Mean Transpolar Drift and Ice Thickness in the Arctic Ocean

open access: yesJournal of Climate, 2019
A theory for the mean ice thickness and the Transpolar Drift in the Arctic Ocean is developed. Asymptotic expansions of the ice momentum and thickness equations are used to derive analytic expressions for the leading-order ice thickness and velocity ...
M. Spall
semanticscholar   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

Weddell Sea iceberg drift: Five years of observations [PDF]

open access: yes, 2006
Since 1999, 52 icebergs have been tagged with GPS buoys in the Weddell Seato enable monitoring of their position. The chosen icebergs were of small tomedium size, with a few icebergs larger than 10 km associatedwith the calving of icebergs A38 and A43 ...
Aoki   +44 more
core   +1 more source

Spring 2021 sea ice transport in the southern Beaufort Sea occurred during coastal-lead opening events [PDF]

open access: yesThe Cryosphere
Winds blew a record large portion of the Arctic's multiyear sea ice (MYI) into the southern Beaufort Sea (SBS) in winter 2021. From early March, a network of buoys from the Sea Ice Dynamic Experiment (SIDEx) tracked the MYI as it drifted across the SBS ...
M. E. Jewell   +2 more
doaj   +1 more source

A coiled‐coil domain triggers oligomerization of MmpL10, the mycobacterial transporter of trehalose polyphleate precursor

open access: yesFEBS Letters, EarlyView.
Most MmpLs transport lipids and glycolipids of the complex mycomembrane of mycobacteria. This study shows that MmpL10 from Mycobacterium smegmatis, the transporter of the trehalose polyphosphate precursor, harbors a coiled‐coil‐like extension. Biochemical and electron microscopy studies demonstrate that the coiled‐coil enables MmpL10 to trimerize.
Julie Couston   +7 more
wiley   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

Thin ice and storms: Sea ice deformation from buoy arrays deployed during N-ICE2015 [PDF]

open access: yes, 2017
Arctic sea ice has displayed significant thinning as well as an increase in drift speed in recent years. Taken together this suggests an associated rise in sea ice deformation rate.
Cheng, Bin   +9 more
core   +2 more sources

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Auf dünnem Eis? Eisdickenänderungen im Nordpolarmeer [PDF]

open access: yes, 2006
While the summer sea ice extent has beendecreasing in the Artic by 8% per decade for the past 30 years,the ice extent has actually increased slightlyin the Antarctic. Ice thickness changes are less well known. In the central Arctic, sea ice thinned by 43%
Haas, Christian
core  

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