Results 1 to 10 of about 4,419 (150)
Anticancer Activity of Natural and Semi-Synthetic Drimane and Coloratane Sesquiterpenoids [PDF]
Molecules, 2022 Drimane and coloratane sesquiterpenoids are present in several plants, microorganisms, and marine life. Because of their cytotoxic activity, these sesquiterpenoids have received increasing attention as a source for new anticancer drugs and pharmacophores.
Lorenz Beckmann +3 more
doaj +6 more sources
Broad-spectrum antifungal activities and mechanism of drimane sesquiterpenoids [PDF]
Microbial Cell, 2020 Eight drimane sesquiterpenoids including (-)-drimenol and (+)-albicanol were synthesized from (+)-sclareolide and evaluated for their antifungal activities.
Edruce Edouarzin +10 more
doaj +5 more sources
Drimane-Type Sesquiterpenoids Derived from the Tropical Basidiomycetes Perenniporia centrali-africana and Cerrena sp. nov [PDF]
Molecules, 2022 Five new drimane-type sesquiterpenoids were isolated from cultures of the tropical basidiomycetes, Perenniporia centrali-africana (originating from Kenya) and Cerrena sp. nov. (originating from Thailand). A new pereniporin A derivative (1), a new drimane-
Paomephan Pathompong +8 more
doaj +3 more sources
Drimane sesquiterpenoids from a wetland soil-derived fungus Aspergillus calidoustus TJ403-EL05 [PDF]
Natural Products and Bioprospecting, 2022 Soil-derived fungi represent an insufficiently tapped reservoir for discovering new and bioactive natural products (NPs), and despite an ever-increasing number of unknown NPs have been discovered over the past few decades, much of the hidden biosynthetic
Sitian Zhang +6 more
doaj +2 more sources
Sesquiterpenoids from the Mangrove-Derived Aspergillus ustus 094102 [PDF]
Marine Drugs, 2022 Four new drimane sesquiterpenoids (1–4) and three known ones (5–7) were isolated from the fermentation broth of the mangrove-derived Aspergillus ustus 094102. Compound 5 was further resolved as four purified compounds 5a–5d.
Pengyan Gui +5 more
doaj +2 more sources
Biosynthesis of Fungal Drimane‐Type Sesquiterpene Esters
Angewandte Chemie, Volume 133, Issue 44, Page 23956-23963, October 25, 2021., 2021 Reported here is the complete elucidation of the biosynthetic pathway of drimane‐type sesquiterpene esters from Aspergillus calidoustus, including the first identified fungal drimenol cyclase. The cluster‐associated acyltransferase is then employed to transfer different lengths of ACP‐activated polyketides, but also very diverse CoA‐esters.
Ying Huang +2 more
wiley +2 more sources
Chemical Diversity and Biosynthesis of Drimane‐Type Sesquiterpenes in the Fungal Kingdom
ChemBioChem, Volume 23, Issue 17, September 5, 2022., 2022 Fungal drimane‐type sesquiterpenes (DTSs) are emerging as a very interesting class of chemicals with many notable activities. Elucidation of DTS biosynthesis in fungi revealed that the two main precursors, drimenol and drim‐8‐ene‐11‐ol, are the preferred backbones.
Ying Huang, Vito Valiante
wiley +1 more source
Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022 Introduction. The Uganda National Drug Authority requires phytochemical screening, freedom from microbial contamination, and evidence of safety and efficacy of the constituent plants to register herbal products. Since Uganda has no pharmacopeia, safety, efficacy, and plant processing information are not readily available.
Bruhan Kaggwa +11 more
wiley +1 more source
Communications Chemistry, 2023 Macrotermitinae termites have farmed fungi in the genus Termitomyces as a food source for millions of years. However, the biochemical mechanisms orchestrating this mutualistic relationship are largely unknown.
Nina B. Kreuzenbeck +13 more
doaj +1 more source
Biomolecules, 2020 Candida species cause an opportunistic yeast infection called Candidiasis, which is responsible for more than 50,000 deaths every year around the world. Effective treatments against candidiasis caused by non-albicans Candida species such as C.
Victor Marin +7 more
doaj +1 more source