Inhibitory Potential of the Drimane Sesquiterpenoids Isotadeonal and Polygodial in the NF-kB Pathway [PDF]
MoleculesInflammation contributes to the onset and development of many diseases, including neurodegenerative diseases, caused by the activation of microglia, leading to neurological deterioration. Nuclear factor-κB (NF-κB) is one of the most relevant pathways for
Víctor Marín +6 more
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Discovery and biosynthesis of bacterial drimane-type sesquiterpenoids from Streptomyces clavuligerus [PDF]
Beilstein Journal of Organic ChemistryDrimane-type sesquiterpenoids (DMTs) are characterized by a distinctive 6/6 bicyclic skeleton comprising the A and B rings. While DMTs are commonly found in fungi and plants, their presence in bacteria has not been reported.
Dongxu Zhang +8 more
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New Drimane Sesquiterpenoids from [PDF]
Natural Product Communications, 2008 From an acetone extract of the aerial parts of Tidestromia oblongifolia (Amaranthaceae), a new drimane sesquiterpenoid bearing an 11,12,13-trihydroxydrimene skeleton (1), as well as the 11,12 acetonide of 1 were isolated.
Sandeep Chaudhary +5 more
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Drimane Sesquiterpenes Isolated from the Fruiting Body of the Clavarioid Fungus Ramaria botrytoides [PDF]
MoleculesFour previously undescribed drimane-type sesquiterpenoids, ramaribotrytols A–D (1–4), were isolated from the fruiting bodies of the clavarioid fungus Ramaria botrytoides.
Gao-Ke Peng +4 more
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Ugandenial A, a New Drimane-type Sesquiterpenoid from Warburgia ugandensis [PDF]
Molecules, 2009 One new drimane-type sesquiterpenoid, named ugandenial A (1), was isolated from the ethyl acetate extract of the bark of Warburgia ugandensis (Canellaceae) together with eight known drimane-type sesquiterpenoids: 11α-hydroxycinnamosmolide (2 ...
Vincent Dumontet +7 more
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SYNTHESIS OF NEW NITROGEN-CONTAINING DRIMANE AND HOMODRIMANE SESQUITERPENOIDS FROM SCLAREOLIDE [PDF]
Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2015 The synthesis of new nitrogen-containing drimane and homodrimane sesquiterpenoids in cycle B is reported. A comparative study of the microwave (MW) assisted synthesis of drimenone versus classical conditions has been done.
Lidia Lungu
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Nanangenines: drimane sesquiterpenoids as the dominant metabolite cohort of a novel Australian fungus, Aspergillus nanangensis [PDF]
Beilstein Journal of Organic Chemistry, 2019 Chemical investigation of an undescribed Australian fungus, Aspergillus nanangensis, led to the identification of the nanangenines – a family of seven new and three previously reported drimane sesquiterpenoids.
Heather J. Lacey +10 more
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Cytotoxic Drimane Sesquiterpenoids Isolated from Perenniporia maackiae
Journal of Natural Products, 2018 A chemical investigation of a basidiomycetes fungus, Perenniporia maackiae, led to the discovery of 12 drimane sesquiterpenoids, including seven new constituents (1–7).
Jae-Jin Kim (533471) +9 more
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Drimane-Type Sesquiterpenoids as Chemosystematic Markers of Canellaceae [PDF]
Journal of the Brazilian Chemical Society, 1999 Polygodial, isopolygodial, mukaadial and polygonone were isolated for the first time from Capsicodendron dinisii. Thus, with respect to drimane-type sesquiterpenoids of the Canellaceae, the close affinity of the South American genus Capsicodendron with ...
Bastos Jairo Kenupp +2 more
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Semisynthetic Derivatives of Polygodial as α-Glucosidase and α-Amylase Inhibitors: In Vitro Evaluation, Molecular Docking and Molecular Dynamics Simulation [PDF]
PharmaceuticsBackground: Polygodial (9), a drimane sesquiterpene dialdehyde from Drimys winteri, has not previously been examined against carbohydrate-hydrolyzing enzymes.
Viviana Burgos +7 more
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