Results 11 to 20 of about 4,039 (229)

9-Deoxymuzigadial, a Sesquiterpene Isolated From Drimys brasiliensis (Winteraceae), Displays Reduced Cytotoxicity In Vitro and Modulates Leukocyte Activity and Fibrogenesis In Vivo. [PDF]

Chem Biodivers
The aims of this study were to investigate in vitro cytotoxic potential and the effects of daily administration during the inflammatory response induced by sponge implants in mice of the sesquiterpene 9‐deoxymuzigadial (9‐DOM), isolated from Drimys ...
Ferreira BA, Cassimiro IS, de Moura FBR, de Campos Lima T, Napolitano DR, Umehara E, Lago JHG, Araújo FA.   +7 more
europepmc   +3 more sources

EDBD-3,6-Epidioxy-1,10-Bisaboladiene-An Endoperoxide Sesquiterpene Obtained from Drimys brasiliensis (Winteraceae) Exhibited Potent Preclinical Efficacy against Schistosoma mansoni Infection. [PDF]

Antibiotics (Basel)
Schistosomiasis, a neglected tropical disease impacting over 250 million individuals globally, remains a major public health challenge due to its prevalence and significant impact on affected communities.
Umehara E, Teixeira TR, Cajás RA, Amaro MC, de Moraes J, Lago JHG.   +5 more
europepmc   +2 more sources

Micromorphological and Chemical Characterization of Drimys winteri Leaf Surfaces: The Secondary Alcohols Forming Epicuticular Wax Crystals Are Accompanied by Alkanediol, Alkanetriol and Ketol Derivatives. [PDF]

Plant Cell Physiol
The cuticle is a hydrophobic coating of most aerial plant surfaces crucial for limiting non-stomatal water loss. Plant cuticles consist of the lipid polyester cutin and associated waxes with compositions varying widely between plant species and organs ...
Zhang Z, Mistry D, Jetter R.
europepmc   +2 more sources

Antimicrobial Activity of Drimanic Sesquiterpene Compounds from Drimys winteri against Multiresistant Microorganisms [PDF]

Molecules
In this work, a group of ten sesquiterpene drimanes, including polygodial (1), isopolygodial (2), and drimenol (3) obtained from the bark of Drimys winteri F. and seven synthetic derivatives, were tested in vitro against a unique panel of bacteria, fungi,
Montenegro I, Pazmiño R, Araque I, Madrid A, Besoain X, Werner E, Espinoza-Catalán L, Olea A, Parra C, Navarrete Molina V, Godoy P, Olguín Y, Cuellar M.   +12 more
europepmc   +2 more sources

Exploring the Therapeutic Potential of Essential Oils of the Valdivian Rainforest (Drimys winteri and Laureliopsis philippiana) for Sustainable Udder Health in Dairy Systems [PDF]

Animals (Basel)
Simple Summary Bovine mastitis is a major health and economic constraint in dairy production and is commonly managed with antibiotics. However, intensive use of these drugs favors antimicrobial resistance, therapeutic failures and residues in milk ...
Vera I, Vera L, Cabrapán D, Ramos P, Ulloa F, Pantoja D, Aranguiz F, Jacobs M, Rojas N, Carretta M, Bruna F, Bravo J, Bahamonde J.   +12 more
europepmc   +2 more sources

Drimanes from Drimys brasiliensis with leishmanicidal and antimalarial activity [PDF]

Memorias do Instituto Oswaldo Cruz, 2013
This paper evaluates CHCl3 and CH3OH extracts of the stem bark, branches and leaves of Drimys brasiliensis and drimane sesquiterpenes isolated from the stem bark against strains of Leishmania amazonensis and Leishmania braziliensis promastigotes and ...
Vanessa Duarte Claudino, Kesia Caroline da Silva, Valdir Cechinel Filho, Rosendo Augusto Yunes, Franco Delle Monache, Alberto Giménez, Efrain Salamanca, David Gutierrez-Yapu, Angela Malheiros   +8 more
doaj   +3 more sources

Exploring the potent antimalarial properties of Drimys beccariana Gibbs through molecular docking analysis utilizing advanced structure-based drug design techniques

Journal of Advanced Pharmaceutical Technology & Research
Original Article Exploring the potent antimalarial properties of Drimys beccariana Gibbs through molecular docking analysis utilizing advanced structure-based drug design techniques Hermanto, Faizal; Ratih, Hestiary1; Alatas, Fikri1; Sutarna, Titta ...
Faizal Hermanto, Hestiary Ratih, Fikri Alatas, Titta Hartyana Sutarna   +3 more
doaj   +2 more sources

Antifungal Effects of Drimane Sesquiterpenoids Isolated from Drimys winteri against Gaeumannomyces graminis var. tritici. [PDF]

Appl Environ Microbiol, 2020
More than two billion tons of pesticides are used every year worldwide. An interesting sustainable alternative to control plant pathogens is the use of natural products obtained from plants, mainly medicinal plants that offer secondary metabolites ...
Paz C, Viscardi S, Iturra A, Marin V, Miranda F, Barra PJ, Mendez I, Duran P.   +7 more
europepmc   +2 more sources

Avaliação da toxicidade aguda, antitumoral e efeitos inibitórios da inflamação aguda de Drimys brasiliensis (Winteraceae)

Revista Contexto & Saúde
O gênero Drimys, pertencente à Família botânica Winteraceae, é amplamente reconhecido e valorizado. Suas espécies têm sido utilizadas na medicina popular para tratar diversos problemas de saúde, como dores gástricas, dor de dente e anemia.
Mariana Cardoso Oshiro, Alícia de Souza Santos, Alisson Macário de Oliveira, Emanuelle Maria da Silva, Helimarcos Nunes Pereira, Jhonatta Alexandre Brito Dias, Marcela Albuquerque de Oliveira, Marília Gabriela Muniz Arruda, Marcilene Souza da Silva, Simone da Paz Leôncio Alves, Ivone Antônia de Souza   +10 more
doaj   +2 more sources

Evaluation of Drimys winteri (Canelo) Essential Oil as Insecticide against Acanthoscelides obtectus (Coleoptera: Bruchidae) and Aegorhinus superciliosus (Coleoptera: Curculionidae). [PDF]

Insects, 2020
Adverse effects caused by synthetic pesticides have increased interest in plant-derived insecticidal compounds, in particular essential oils, as a more compatible and ecofriendly alternative for pest control of economic importance.
Tampe J, Espinoza J, Chacón-Fuentes M, Quiroz A, Rubilar M.   +4 more
europepmc   +2 more sources