Results 1 to 10 of about 27,906 (156)

9-Deoxymuzigadial, a Sesquiterpene Isolated From Drimys brasiliensis (Winteraceae), Displays Reduced Cytotoxicity In Vitro and Modulates Leukocyte Activity and Fibrogenesis In Vivo. [PDF]

Chem Biodivers
The aims of this study were to investigate in vitro cytotoxic potential and the effects of daily administration during the inflammatory response induced by sponge implants in mice of the sesquiterpene 9‐deoxymuzigadial (9‐DOM), isolated from Drimys ...
Ferreira BA, Cassimiro IS, de Moura FBR, de Campos Lima T, Napolitano DR, Umehara E, Lago JHG, Araújo FA.   +7 more
europepmc   +3 more sources

In Vitro and In Vivo Evaluation of the Antischistosomal Activity of Polygodial and 9-Deoxymuzigadial Isolated from Drimys brasiliensis Branches [PDF]

Molecules
In the present study, the hexane extract from branches of Drimys brasiliensis (Winteraceae) displayed potent activity against Schistosoma mansoni parasites (100% mortality of the worms at 200 μg/mL). Bioactivity-guided fractionation afforded, in addition
Eric Umehara, Rayssa A. Cajas, Gabriel B. Conceição, Guilherme M. Antar, Adriano D. Andricopulo, Josué de Moraes, João Henrique G. Lago   +6 more
doaj   +3 more sources

Anti-Trypanosoma cruzi Effects of Sesquiterpenoids from Branches of Drimys brasiliensis (Winteraceae) [PDF]

ACS Omega
The hexane extract of Drimys brasiliensis (Winteraceae) branches displayed activity against trypomastigote forms of Trypanosoma cruzi and was subjected to a bioactivity-guided fractionation procedures to afford four bisabolenerel-(3S,7R)-3-hydroxy ...
Eric Umehara, Dayana A. S Ferreira, Mariana B. Abiuzi, Myron Christodoulides, Ravi Kant, Andre G. Tempone, João Henrique G. Lago   +6 more
doaj   +3 more sources

Drimanes from Drimys brasiliensis with leishmanicidal and antimalarial activity [PDF]

Memorias do Instituto Oswaldo Cruz, 2013
This paper evaluates CHCl3 and CH3OH extracts of the stem bark, branches and leaves of Drimys brasiliensis and drimane sesquiterpenes isolated from the stem bark against strains of Leishmania amazonensis and Leishmania braziliensis promastigotes and ...
Vanessa Duarte Claudino, Kesia Caroline da Silva, Valdir Cechinel Filho, Rosendo Augusto Yunes, Franco Delle Monache, Alberto Giménez, Efrain Salamanca, David Gutierrez-Yapu, Angela Malheiros   +8 more
doaj   +3 more sources

EDBD—3,6-Epidioxy-1,10-Bisaboladiene—An Endoperoxide Sesquiterpene Obtained from Drimys brasiliensis (Winteraceae) Exhibited Potent Preclinical Efficacy against Schistosoma mansoni Infection [PDF]

Antibiotics
Schistosomiasis, a neglected tropical disease impacting over 250 million individuals globally, remains a major public health challenge due to its prevalence and significant impact on affected communities.
Eric Umehara, Thainá R. Teixeira, Rayssa A. Cajás, Monique C. Amaro, Josué de Moraes, João Henrique G. Lago   +5 more
doaj   +3 more sources

Comparison of leaf anatomy and essential oils from Drimys brasiliensis Miers in a montane cloud forest in Itamonte, MG, Brazil. [PDF]

Bot Stud, 2014
Background: Drimys brasiliensis Miers is native to Brazil, where it is mainly found in montane forests and flooded areas in the South and Southeast regions of the country.
Cruz BPD, de Castro EM, Cardoso MDG, de Souza KF, Machado SMF, Pompeu PV, Fontes MAL.   +6 more
europepmc   +5 more sources

Drimys brasiliensis essential oil as a source of drimenol [PDF]

Holos, 2016
Drimys brasiliensis Miers is a native plant species to the Atlantic Forest, commonly known as cataia, and used as a stimulant, anti-diahrreal, antipyretic, among other properties.
Luciele Milani Zem, Katia Christina Zuffellato-Ribas, Henrique Soares Koehler, Maria Izabel Radomski, Cicero Deschamps   +4 more
doaj   +4 more sources

Avaliação da toxicidade aguda, antitumoral e efeitos inibitórios da inflamação aguda de Drimys brasiliensis (Winteraceae) [PDF]

Revista Contexto & Saúde
O gênero Drimys, pertencente à Família botânica Winteraceae, é amplamente reconhecido e valorizado. Suas espécies têm sido utilizadas na medicina popular para tratar diversos problemas de saúde, como dores gástricas, dor de dente e anemia.
Mariana Cardoso Oshiro, Alícia de Souza Santos, Alisson Macário de Oliveira, Emanuelle Maria da Silva, Helimarcos Nunes Pereira, Jhonatta Alexandre Brito Dias, Marcela Albuquerque de Oliveira, Marília Gabriela Muniz Arruda, Marcilene Souza da Silva, Simone da Paz Leôncio Alves, Ivone Antônia de Souza   +10 more
doaj   +4 more sources

ASPECTOS DA BIOLOGIA REPRODUTIVA DE Drimys brasiliensis Miers (WINTERACEAE) EM FLORESTA OMBRÓFILA MISTA, SUL DO BRASIL [PDF]

Ciência Florestal, 2014
Drimys brasiliensis Miers, conhecida como cataia ou casca-de-anta, é uma árvore nativa da Floresta Ombrófila Mista. Sua casca tem sido utilizada medicinalmente a partir da exploração de árvores em populações naturais.
Alexandre Mariot, Adelar Mantovani, Ricardo Bittencourt, Maurício Sedrez dos Reis   +3 more
doaj   +5 more sources

Anti-lipid Potential of Drimys brasiliensis. [PDF]

Pharmacogn Mag, 2017
Background: The traditional use of Drimys brasiliensis Miers (Winteraceae) in the south of Brazil to reduce cholesterol has not been described in scientific literature. Objective: To verify the hypocholesterolemic effects of D. brasiliensis using rats as
Merotto J, Cestonaro LV, Rossato-Grando LG, de Oliveira Siqueira L, Bertol CD.   +4 more
europepmc   +2 more sources