Results 141 to 150 of about 27,917 (167)

Sesquiterpene Polygodial from Drimys brasiliensis (Winteraceae) Down-Regulates Implant-Induced Inflammation and Fibrogenesis in Mice.

Journal of Natural Products, 2020
Drimys brasiliensis (Winteraceae) has been investigated in traditional medicine for its anti-inflammatory properties to treat gastric ulcers and allergic and respiratory system diseases as well as for cancer treatment.
B. Ferreira, Anderson Ferraz Norton Filho, S. R. Deconte, T. Tomiosso, Fernanda Thevenard, S. P. Andrade, J. Lago, F. Araújo   +7 more
semanticscholar   +1 more source

Antitrypanosomal activity of epi-polygodial from Drimys brasiliensis and its effects in cellular membrane models at the air-water interface.

Bioorganic chemistry (Print), 2019
Epi-polygodial, a drimane sesquiterpene was isolated from Drimys brasiliensis (Winteraceae). This compound demonstrated high parasite selectivity towards Trypanosoma cruzi trypomastigotes (IC50 = 5.01 μM) with a selectivity index higher than 40.
Giulia E G Gonçalves, Thiago R. Morais, Kaio S. Gomes, T. Costa-Silva, A. Tempone, J. Lago, L. Caseli   +6 more
semanticscholar   +1 more source

Antiproliferative and toxicological properties of drimanes obtained from Drimys brasiliensis stem barks.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018
Stem barks of Drimys brasiliensis (Winteraceae) are consumed by the population in the form of a condiment. It is widely used to treat gastric and stomach problems and also to treat cancer. The extracts have demonstrated antiproliferative, antileishmanial
Eduarda Fratoni, A. E. de Athayde, M. da Silva Machado, T. Zermiani, I. Venturi, Matheus Corrêa dos Santos, F. Lobato, V. Cechinel Filho, G. Franchi, A. Nowill, J. R. Santin, A. Malheiros   +11 more
semanticscholar   +1 more source

Molecular Modeling of Substances Isolated from the Essential Oil of the Species Drimys angustifolia and Drimys brasiliensis

, 2020
Carry out an in silico study of chemical substances isolated from the species: Drimys angustifolia and Drimys brasiliensis. A theoretical study of global reactivity, QSAR descriptors, MEP construction and molecular docking was performed to analyze ...
Neuziane Dias Conceição, L. R. de Souza, J. V. Ferreira, Maiara de Fátima Brito Brito, A. A. Pinheiro, Karina Rufino da Silva, C. Taft, C. H. T. de Paula da Silva, Madson Ralide Fonseca Gomes, Lorane Izabel da Silva Hage-Melim   +9 more
semanticscholar   +1 more source

EXPLORAÇÃO DO POTENCIAL TERAPÊUTICO DO SESQUITERPENO ENDOPERÓXIDO DE DRIMYS BRASILIENSIS NO TRATAMENTO DA ESQUISTOSSOMOSE

Anais do V Congresso Acadêmico e Tecnológico da Universidade Brasil
As doenças negligenciadas provocadas por helmintos, como a esquistossomose, continuam a afetar milhões de pessoas em todo o mundo, especialmente em áreas tropicais e subtropicais.
Thainá Rocha Teixeira, E. Umehara, Rayssa Araujo Cajás, João Henrique Guilhardi Lago, Josué de Moraes   +4 more
semanticscholar   +1 more source

Using molecular networking and docking to explore arginase inhibitors among Drimys brasiliensis chemical constituents

Medicinal Chemistry Research, 2023
L. Mendes, T. B. V. Dantas, R. Severino, L. R. G. da Silva, D. D. de Souza, Q. Cass, S. Ramalho, P. Vieira, G. D. de Souza, R. Guido, Marie-Kathrin Urschel, C. Kersten, L. D. de Sousa   +12 more
semanticscholar   +1 more source

Genetic diversity and structure of Drimys brasiliensis in southern Brazil: insights for conservation

Journal of Forest Research, 2019
A. Mariot, T. Montagna, M. Reis
semanticscholar   +2 more sources

Sporothrix brasiliensis: A Review of an Emerging South American Fungal Pathogen, Its Related Disease, Presentation and Spread in Argentina

Journal of Fungi (Basel, Switzerland), 2021
Alejandro Nazareno Etchecopaz, Maria Agustina Toscanini, Alejandro D Nusblat   +2 more
exaly  

Insecticidal activity, toxicity and biochemical alterations of Drimys brasiliensis essential oil against Spodoptera frugiperda

Journal of Pest Science
Greissi Tente Giraldi, W. do Amaral, R. C. Zimmermann, Edson José Mazarotto, A. M. Schafaschek, Alisson Esser Gerber, B. H. L. N. S. Maia, Elaine Fernanda Dos Santos, Mário Antônio Navarro da Silva, Luis Amilton Foester   +9 more
semanticscholar   +1 more source

Further drimane sesquiterpenes from Drimys brasiliensis stem barks with cytotoxic potential

Naunyn-Schmiedeberg's Archives of Pharmacology, 2016
Eduarda Fratoni, V. D. Claudino, R. Yunes, Gilberto C. Jr. Franchi, A. Nowill, V. Filho, F. Monache, A. Malheiros   +7 more
semanticscholar   +1 more source