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EXPLORAÇÃO DO POTENCIAL TERAPÊUTICO DO SESQUITERPENO ENDOPERÓXIDO DE DRIMYS BRASILIENSIS NO TRATAMENTO DA ESQUISTOSSOMOSE

Anais do V Congresso Acadêmico e Tecnológico da Universidade Brasil
As doenças negligenciadas provocadas por helmintos, como a esquistossomose, continuam a afetar milhões de pessoas em todo o mundo, especialmente em áreas tropicais e subtropicais. Causando impactos significativos na saúde pública, comprometendo a educação e o desenvolvimento socioeconômico das regiões afetadas.
Thainá Rocha Teixeira +4 more
openaire +1 more source

Antitrypanosomal activity of epi-polygodial from Drimys brasiliensis and its effects in cellular membrane models at the air-water interface

Bioorganic Chemistry, 2019
Epi-polygodial, a drimane sesquiterpene was isolated from Drimys brasiliensis (Winteraceae). This compound demonstrated high parasite selectivity towards Trypanosoma cruzi trypomastigotes (IC50 = 5.01 μM) with a selectivity index higher than 40. These results were correlated with the effects observed when this compound was incorporated in cellular ...
Giulia Elisa Guimarães, Gonçalves +6 more
openaire +2 more sources

Biomedical applications of natural rubber latex from the rubber tree Hevea brasiliensis

Materials Science and Engineering C, 2021
Nayrim B. Guerra +2 more
exaly

Using molecular networking and docking to explore arginase inhibitors among Drimys brasiliensis chemical constituents