Results 211 to 220 of about 2,188,260 (386)
Advanced Science, EarlyView.This research integrated multi‐omics analysis of bone tissue from HLU and control mice revealed that mechanical unloading suppresses intrinsic apoptosis and augments glutamine (Gln) catabolism in osteoclast lineage cells. The findings highlight pivotal roles for SLC1A5‐mediated Gln metabolism and XIAP/Diablo axis‐mediated apoptosis suppression.
Yi Ding +14 more
wiley +1 more source
Personal perceptions of risky drinking and alcohol guidelines - a qualitative analysis. [PDF]
BMC Public HealthCrawford J +3 more
europepmc +1 more source
The Oppenheimer Drink-cure in Bellevue Hospital and Gen. O'Beirne's Letter. [PDF]
, 1896 Justitia
openalex +1 more source
Advanced Science, EarlyView.USP13 deficiency in intestinal epithelial cells aggravates DSS‐induced colitis by enhancing ER stress and apoptosis. USP13 interacts with GRP78 and reduces its K63‐linked ubiquitination to alleviate epithelial injury. Restoring USP13 expression or targeting the USP13‐GRP78 axis may represent a promising strategy for treating inflammatory bowel disease ...
Chenchen Qian +9 more
wiley +1 more source
Capturing meaningful change: Initiation and maintenance of reductions in World Health Organization risk drinking levels among mandated college students. [PDF]
Psychol Addict BehavReid AE, Carey KB, Witkiewitz K.
europepmc +1 more source
Advanced Science, EarlyView.Cadmium, a carcinogenic heavy metal, drives breast cancer progression via metabolic reprogramming and autophagic flux disruption. Multi‐omics revealed cadmium‐induced 5'‐methylthioadenosine depletion activates DOT1L‐mediated H3K79me1 at PAK2 promoter, upregulating PAK2 to block autophagy and driving malignancy. Clinically, 5'‐methylthioadenosine levels
Jingdian Li +24 more
wiley +1 more source
Exploring othering and perceived harmful drinking contexts among risky drinkers: An arts-based focus group study. [PDF]
Br J Health PsycholOldham M +8 more
europepmc +1 more source