Results 221 to 230 of about 879,918 (311)

A pilot evaluation of managed alcohol programs operating in the context of the COVID-19 pandemic. [PDF]

Harm Reduct J
Goulet-Stock S, Stockwell T, Brown M, Rautenberg D, Pauly B.   +4 more
europepmc   +1 more source

Akkermansia Muciniphila Alleviates Severe Acute Pancreatitis via Amuc1409‐Ube2k‐Foxp3 Axis in Regulatory T Cells

Advanced Science, EarlyView.
Akkermansia depletion correlates with acute pancreatitis (AP) severity. A. muciniphila and its protein Amuc_1409 mitigate pancreatic/systemic inflammation by expanding Tregs and IL‐10. Mechanistically, Amuc_1409 binds Ube2k, inhibiting Foxp3 ubiquitination to stabilize Treg differentiation and IL‐10 production, countering SAP‐induced SIRS/CARS ...
Jinyan Xie, Lijun Du, Yunkun Lu, Xiuliu Guo, Xinyuan Zhou, Yifan Tong, Bo Shen, Xin Yu, Feng Guo, Hong Yu   +9 more
wiley   +1 more source

Defining “drinking culture”: A critical review of its meaning and connotation in social research on alcohol problems

, 2016
M. Savic, R. Room, Janette Mugavin, A. Pennay, M. Livingston   +4 more
semanticscholar   +1 more source

Apremilast reduces co-occurring alcohol drinking and mechanical allodynia and regulates central amygdala GABAergic transmission. [PDF]

JCI Insight
Vozella V, Borgonetti V, Cruz B, Onge CMS, Bullard R, Vlkolinsky R, Ceballos DG, Ozburn AR, Roberts AJ, Ciccocioppo R, Bajo M, Roberto M.   +11 more
europepmc   +1 more source

Microbial Biosensor for Sensing and Treatment of Intestinal Inflammation

Advanced Science, EarlyView.
The engineered calprotectin biosensor detects gut inflammation, processes the signal through genetic regulation, and responds by expressing the reporter sfGFP and the therapeutic protein secIL10. This dual functionality enables the engineered biosensor not only to sense but also to mitigate gut inflammation, highlighting its potential for disease ...
Duolong Zhu, Jeffrey Galley, Jason Pizzini, Elena Musteata, Martin V. Douglas, Walter J. Chazin, Eric P. Skaar, Jeffrey J. Tabor, Robert A. Britton   +8 more
wiley   +1 more source

Moving Beyond the Silos of Opportunistic Pathogen and Disinfection Byproduct Research to Improve Drinking Water System Management. [PDF]

Environ Sci Technol
Lee S, Sun Y, Fan S, Rahim N, Xian Y, Shakhawat MK, Chavarria KA, Vedrin M, Guikema S, Sela L, Kumpel E, Lanzarini-Lopes M, Shen Y, Kirisits MJ, Raskin L, Potgieter S, Dowdell KS, Szczuka A.   +17 more
europepmc   +1 more source

Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset

Advanced Science, EarlyView.
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu, Zhengyuan Zhou, Sascha Schäuble, Wolfgang Vivas, Karen Dlubatz, Michael Bauer, Sebastian Weis, Mervyn Singer, Roman Lukaszewski, Gianni Panagiotou   +9 more
wiley   +1 more source

Longitudinal analysis for between- and within-person influences of descriptive alcohol drinking norms and attitudes on drinking outcomes. [PDF]

Alcohol Clin Exp Res (Hoboken)
DiBello AM, Miller MB, Hatch MR, Mastroleo NR, Carey KB.   +4 more
europepmc   +1 more source

Natural Fiber@MXene‐Engineered Chitosan Aerogels: Thermodynamic‐Transport Synergy for Solar‐Driven Hypersaline Interfacial Evaporation

Advanced Science, EarlyView.
The natural fiber@MXene‐engineered chitosan aerogel with hierarchically oriented channels is developed in this study. The photon‐entrapping networks cooperated with oriented channels to facilitate water transport and improve solar‐thermal/environmental energy synergy, endowing an evaporation rate up to 4.40 kg m−2 h−1 and efficient salt rejection ...
Qin Su, Haidi Wu, Suyang Hou, Liping Ye, Yifan Feng, Longjuan Lu, Biwang Pan, Wancheng Gu, Longcheng Tang, Xuewu Huang, Huaiguo Xue, Jiefeng Gao   +11 more
wiley   +1 more source