Abstract Purpose This study evaluates whether mesopic microperimetry (MMP) provides a more robust measure of retinal function compared to visual acuity (VA) in age‐related macular degeneration (AMD) clinical trials, with a focus on optimal analysis strategies. Method Fellow‐eyes of unilateral neovascular AMD were prospectively studied.
Francesco Cinque +9 more
wiley +1 more source
Excessive manganese content in children's multivitamin supplements: Potential for neurodevelopmental harm and other adverse health outcomes. [PDF]
Frisbie SH +4 more
europepmc +1 more source
Abstract Purpose To study ocular fundus morphology and its relation to growth in adolescents born moderate‐to‐late preterm (MLP) and full term. Methods This prospective and population‐based cohort study included 50 MLP adolescents (26 girls, mean age 16.5 years) and 50 full‐term controls (30 girls, mean age 16.7 years).
Alexandra Lind +6 more
wiley +1 more source
Key Nutrient Intakes at Risk Among US Children in the National Health and Nutrition Examination Survey (NHANES) 2015-2016 Stratified by Age and Gender. [PDF]
Lasekan J +4 more
europepmc +1 more source
Multiscale Approximations to Understand the Complex Role of Microglia in Alzheimer's Disease
Microglia are dynamic, context‐dependent regulators of Alzheimer's disease, modulating amyloid, tau, and neurodegeneration across disease stages. Integrating multiscale and human‐focused approaches is essential to translate microglial biology into therapeutic strategies. ABSTRACT Microglia, the resident innate immune cells of the central nervous system,
Patricia Martínez‐Tazo +9 more
wiley +1 more source
Association of magnesium deficiency, tobacco smoke exposure and hypertension in children and adolescents: evidence from the NHANES 2007-2018. [PDF]
Gong Y, Zhou C, Wan Y, Yin H.
europepmc +1 more source
Proteomic Trajectories of Metabolic and Proteostatic Adaptation During Normothermic Liver Perfusion
ABSTRACT Background Normothermic machine perfusion (NMP) enables metabolic restoration and viability testing of liver grafts, but current viability criteria incompletely predict post‐transplant outcomes. The molecular basis of graft resilience or biliary vulnerability remains unclear. This study aimed to characterise tissue‐level proteomic trajectories
Heithem Jeddou +10 more
wiley +1 more source
Orchestrating Spatial Transcriptomics Analysis with Bioconductor
Crowell HL +33 more
europepmc +1 more source
Pressure-induced stromal keratopathy (PISK) from the slit lamp to the optical coherence tomography (OCT). [PDF]
López LÁC +4 more
europepmc +1 more source
Autoactive MtDMI1 Reprogrammes Immunity and Development in Tomato via Ethylene Signalling
ABSTRACT The Common Symbiosis Signalling Pathway (CSSP) underpins interactions between plants and microbes, yet its potential for crop improvement remains underexplored. Here, we investigated the gain‐of‐function mutant SPD1 (MtDMI1S760N), which constitutively activates the symbiotic signalling pathway in Medicago truncatula, by expressing it in tomato
Haiyue Liu, Ji Xu, Fang Xie
wiley +1 more source

