Results 151 to 160 of about 24,012 (230)

Power and clinical utility of mesopic microperimetry analysis strategies in age‐related macular degeneration

open access: yesActa Ophthalmologica, Volume 104, Issue 3, Page e292-e299, May 2026.
Abstract Purpose This study evaluates whether mesopic microperimetry (MMP) provides a more robust measure of retinal function compared to visual acuity (VA) in age‐related macular degeneration (AMD) clinical trials, with a focus on optimal analysis strategies. Method Fellow‐eyes of unilateral neovascular AMD were prospectively studied.
Francesco Cinque   +9 more
wiley   +1 more source

Exploring ocular fundus morphology in relation to growth in adolescents born moderate‐to‐late preterm

open access: yesActa Ophthalmologica, Volume 104, Issue 3, Page e346-e355, May 2026.
Abstract Purpose To study ocular fundus morphology and its relation to growth in adolescents born moderate‐to‐late preterm (MLP) and full term. Methods This prospective and population‐based cohort study included 50 MLP adolescents (26 girls, mean age 16.5 years) and 50 full‐term controls (30 girls, mean age 16.7 years).
Alexandra Lind   +6 more
wiley   +1 more source

Multiscale Approximations to Understand the Complex Role of Microglia in Alzheimer's Disease

open access: yesEuropean Journal of Neuroscience, Volume 63, Issue 9, May 2026.
Microglia are dynamic, context‐dependent regulators of Alzheimer's disease, modulating amyloid, tau, and neurodegeneration across disease stages. Integrating multiscale and human‐focused approaches is essential to translate microglial biology into therapeutic strategies. ABSTRACT Microglia, the resident innate immune cells of the central nervous system,
Patricia Martínez‐Tazo   +9 more
wiley   +1 more source

Proteomic Trajectories of Metabolic and Proteostatic Adaptation During Normothermic Liver Perfusion

open access: yesLiver International, Volume 46, Issue 5, May 2026.
ABSTRACT Background Normothermic machine perfusion (NMP) enables metabolic restoration and viability testing of liver grafts, but current viability criteria incompletely predict post‐transplant outcomes. The molecular basis of graft resilience or biliary vulnerability remains unclear. This study aimed to characterise tissue‐level proteomic trajectories
Heithem Jeddou   +10 more
wiley   +1 more source

Orchestrating Spatial Transcriptomics Analysis with Bioconductor

open access: yes
Crowell HL   +33 more
europepmc   +1 more source

Autoactive MtDMI1 Reprogrammes Immunity and Development in Tomato via Ethylene Signalling

open access: yesPlant Biotechnology Journal, Volume 24, Issue 5, Page 2861-2875, May 2026.
ABSTRACT The Common Symbiosis Signalling Pathway (CSSP) underpins interactions between plants and microbes, yet its potential for crop improvement remains underexplored. Here, we investigated the gain‐of‐function mutant SPD1 (MtDMI1S760N), which constitutively activates the symbiotic signalling pathway in Medicago truncatula, by expressing it in tomato
Haiyue Liu, Ji Xu, Fang Xie
wiley   +1 more source

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