Results 91 to 100 of about 5,874,199 (333)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Hydraulic system provides smooth control of large tracking and antenna drive systems at very low tracking rates [PDF]

open access: yes, 1967
Hydraulic system provides smooth control of large tracking and antenna drive systems at very low tracking rates. This configuration modifies a series connection of the drive motors with compensating orifices to offset the effects of drain line loss ...
Parker, G. L.
core   +1 more source

Opinion: Standardizing the definition of gene drive

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2020
Gene drive has become a hot topic in the popular press and the scientific literature, yet little consensus vocabulary on the subject exists. As members of the gene drive community, we have developed a core set of definitions to help stakeholders discuss ...
L. Alphey   +3 more
semanticscholar   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Extended Driving Impairs Nocturnal Driving Performances

open access: yesPLoS ONE, 2008
Though fatigue and sleepiness at the wheel are well-known risk factors for traffic accidents, many drivers combine extended driving and sleep deprivation. Fatigue-related accidents occur mainly at night but there is no experimental data available to determine if the duration of prior driving affects driving performance at night. Participants drove in 3
Patricia Sagaspe   +7 more
openaire   +3 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A neuroanatomical basis for electroacupuncture to drive the vagal–adrenal axis

open access: yesNature, 2021
Shenbin Liu   +8 more
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Synthesis of Optimal Dynamic Mode of Manipulator Boom Movement Mounted on Elastic Base

open access: yesНаука и техника, 2019
In order to increase reliability and accuracy of robot manipulators or other construction equipment used for lifting operations an optimum dynamic mode for moving its boom system has been calculated in the paper.
V. S. Loveikin, D. A. Mischuk
doaj   +1 more source

Enhancer features that drive formation of transcriptional condensates

open access: yesbioRxiv, 2018
Enhancers, DNA elements that regulate gene expression, contain transcription factor (TF) binding sites. TFs bind short sequence motifs that are present throughout the genome at much higher frequency than active enhancers, and so the features that define ...
Krishna Shrinivas   +10 more
semanticscholar   +1 more source

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