Results 111 to 120 of about 2,007,083 (298)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
, 2011 This book section is from Auto motives : understanding car use behaviours: Our global reliance on private automobiles as the primary means for transporting individuals is likely to become of increasing political importance over the next ten to twenty years.
openaire +3 more sources
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Apunts: Educación Física y Deportes, 2010 A pesar del interés emergente en el acondicionamiento físico en el golf, se han llevado a cabo pocos estudios para valorar la relación entre la potencia mecánica y el rendimiento en golf. El objetivo de este estudio fue valorar si existía una correlación
Lorena Torres Ronda +3 more
doaj
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Mathematical Modelling of Hybrid Powertrain Systems for Improved Energy Efficiency
CommunicationsThe development and simulation of a mathematical model for a hybrid powertrain vehicle, aiming to optimize its energy efficiency and dynamic performance is presented in this study.
Oleg Lyashuk +8 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
, 1953 Video footage from the WBAP-TV station in Fort Worth, Texas to accompany a news story about a parade at Southern Methodist University promoting the school's annual Red Cross blood drive, also sponsored by the local ...
WBAP-TV (Television station : Fort Worth, Tex.)
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
A stationary bench simulating the traction drive of electric transport vehicles in the traction and braking modes is employed in investigation of the drive operation with a hybrid energy storage system. The load simulator of the traction drive is made by
Zaļeskis, Genadijs +3 more
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