Results 121 to 130 of about 4,883,918 (257)
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
NUEVE NOTAS SOBRE EL CONCEPTO DE PULSIÓN EN LA OBRA DE J. LACAN
Affectio Societatis, 2015 This paper is intended as an introductory review of the concept of drive in Lacan's work. This notion is central to psychoanalytic theory and clinic; therefore, it is always convenient to recall the novelties introduced by Lacan on this topic.
Bruno Bonoris
doaj
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Leaf metabolites drive the functional composition of the phyllosphere microbiome in tea plants
Beverage Plant ResearchThe phyllosphere microbiome is a complex and dynamic community that influences plant growth and health. However, the mechanisms underlying the functional assembly of the phyllosphere microbiome driven by host metabolites remain largely elusive.
Xiangfeng Tan +4 more
doaj +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Механика машин, механизмов и материалов, 2019 A mathematical model of the load of the shearer drive of the drum type cutting unit is introduced. It takes into account the speed of its movement, the angular speed of rotation of the cutting unit, the taper angle of the cutting part and the number of ...
Alexander S. Romanovich +1 more
doaj
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Drive program documentation [PDF]
The program description and user's guide for the Downlist Requirement Integrated Verification and Evaluation (DRIVE) program is provided.
Graham, S.
core +1 more source