Results 151 to 160 of about 5,874,199 (333)
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
NUEVE NOTAS SOBRE EL CONCEPTO DE PULSIÓN EN LA OBRA DE J. LACAN
This paper is intended as an introductory review of the concept of drive in Lacan's work. This notion is central to psychoanalytic theory and clinic; therefore, it is always convenient to recall the novelties introduced by Lacan on this topic.
Bruno Bonoris
doaj
Leaf metabolites drive the functional composition of the phyllosphere microbiome in tea plants
The phyllosphere microbiome is a complex and dynamic community that influences plant growth and health. However, the mechanisms underlying the functional assembly of the phyllosphere microbiome driven by host metabolites remain largely elusive.
Xiangfeng Tan +4 more
doaj +1 more source
Driving: Pre-Cognition and Driving [PDF]
The most significant recent developments in the study of car travel have come from mobility studies rather than the long dominant field of transport psychology (Cresswell 2006; Hannam et al. 2006; Sheller and Urry 2006). In sociology John Urry (2000, 2004) has argued that we need to rethink how we conceptualise society in tandem with how we ...
openaire +1 more source
Multi-faceted particle pumps drive carbon sequestration in the ocean
P. Boyd +4 more
semanticscholar +1 more source
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
The Common Drive Unit (CDU) is a high reliability rotary actuator with many versatile applications in mechanism designs. The CDU incorporates a set of redundant motor-brake assemblies driving a single output shaft through differential.
Ellis, R. C., Fink, R. A., Moore, E. A.
core +1 more source
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source

