Results 151 to 160 of about 2,007,083 (298)

Acetazolamide to prevent ventilatory drive withdrawal in REM sleep apnoea: a randomised controlled trial. [PDF]

Thorax
Messineo L, Kim M, Azarbarzin A, Vena D, Preuss M, Esmaeili N, Aishah A, Lawrence NV, Gilbertson DC, White DP, Wellman A, Sands SA.   +11 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

HazAPP: Study protocol of a randomized controlled trial to enhance parental instruction of teens' hazard anticipation skill during the learner phase of licensure. [PDF]

Inj Epidemiol
O'Neal EE, Mucciolo E, Rokke-Smith G, Swanson B.   +3 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

DRIVE IN 2

, 2011
The DRIVE IN2 Project aims to focus on the definition of methodologies, technologies and advanced and innovative systems on the interaction between the driver and the vehicle in order to prevent road accidents and reduce the emissions of polluting agents.
CESARELLI, MARIO
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Arthropod-Inspired Miniature Modular Vibration Direct-Drive Robot With Untethered Locomotion. [PDF]

Adv Sci (Weinh)
Zhang S, Liu Z, Liu Y, Wang D, Liu Y.
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Diabetes and Driving [PDF]

Canadian Journal of Diabetes, 2018
Robyn L, Houlden, Lori, Berard, Joshua M, Lakoff, Vincent, Woo, Jean-François, Yale   +4 more
openaire   +2 more sources

Finding the perfect promoter for Cas9 in homing gene drives using single cell transcriptome data. [PDF]

Nat Commun
Wu Y, Xia Y, Yao Z, Chen W, Jia X, Liang N, Champer J.   +6 more
europepmc   +1 more source