Results 231 to 240 of about 2,007,083 (298)

Theory and evidence of amplitude control by frequency detuning in a coupled neuronal oscillator system. [PDF]

PLoS Comput Biol
Lu AC, Ourang SA, Moore JD.
europepmc   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Constant-Envelope Waveform Design and Phase Recovery for Integrated Sensing and Communication in High-Mobility Multipath Environments. [PDF]

Sensors (Basel)
Xue W, Chen P, Li C, Cao Z, Zhang S.
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

What's lurking within: When retroperitoneal calciphylaxis goes off-skin. [PDF]

Radiol Case Rep
Cho H, Sommer D, Tran B, Dimowo O, O'Connell R, Reddy U, Houshyar R.   +6 more
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Receipt of glucagon-like peptide-1 receptor agonists among rural patients with obstructive sleep apnea and excess weight. [PDF]

Ann Am Thorac Soc
Leonhard AG, Josey K, Castaneda JM, Chee M, Duan KI, Nadeem H, Plumley R, Triplette M, Smith NL, Au DH, Feemster LC, Donovan LM.   +11 more
europepmc   +1 more source

Considerations for Postrelease Environmental Safety Monitoring of Gene Drive-Modified Mosquitoes as a Tool for Malaria Control in Sub-Saharan Africa. [PDF]

Am J Trop Med Hyg
Abram PK, Bouyer J, Dass B, Ogoyi D, Okumu F, Overcash J, James SL.   +6 more
europepmc   +1 more source

Joint Latent Profile Analysis of BIS/BAS and Self-Control Systems in Gender Differences of Internet Gaming Disorder Among Chinese University Students: The Mediating Role of Anxiety and Depression in a Cross-Sectional Study. [PDF]

Psychol Res Behav Manag
Zhang Z, Song P, Wu J, Gao Y, Wang L, Li H, Wang Y, Quan W, Zhang J, Fang Y, Xu Z, Zhong N, Li Y, Jiao D.   +13 more
europepmc   +1 more source