Results 151 to 160 of about 309,624 (329)

Model of contact between rollers and sprockets in chain-drive systems

, 2005
A model of a roller-chain drive is developed and applied to the simulation and analysis of roller-chain drives of large marine diesel engines. Two different ways of modelling the contact between the rollers and sprockets are presented; one using a ...
Pedersen, Sine Leergaard
core  

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

A conceptual field-based framework for lower-upper body kinetic chain assessment in the tennis serve using IMUs and portable force plates: measurement coverage, new performance indices, and applied implications. [PDF]

Front Sports Act Living
Kwon JW.
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Methods of defining friction moument in chain drive unit

, 1999
Подані способи і конструкції стендів та методики для визначення моменту тертя в шарнірах приводних ланцюгів і коефіцієнта корисної дії в ланцюгових передачах.Methods of stand construction and techniques for defining friction moment in drive chains ...
Попов, В. Л., Popov, V., Roganov, L., Попов, Всеволод Леонідович, Роганов, Лев Леонідович, Роганов, Л. Л.   +5 more
core  

A multimodal spatio-temporal graph neural network framework for fatigue detection in tennis serving. [PDF]

Front Bioeng Biotechnol
Yuan Y, Wang L, Jia H, Jiao J.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Vibrodiagnostic investigations at a chain drive stand of a sucker rod well pump

, 2018
Актуальность исследования. В настоящее время применение штанговых скважинных насосных установок является наиболее простым и надежным способом добычи нефти.
Zubairov, Sibagat Garifovich, Зубаиров, Сибагат Гарифович, Ямалиев, Виль Узбекович, Yamaleev, Ville Uzbekovich, Lenkov, Stanislav Nikolaevich, Ленков, Станислав Николаевич   +5 more
core