Results 131 to 140 of about 309,624 (329)

A Three R Approach for Supply Chain Business Intelligence

open access: yes, 2007
Today, manufacturing enterprises are required to improve their competitive performance by establishing effective controls over the complex processes and datasets, both internal and external, which drive their business.
Little, David   +3 more
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Supply chain management tools and methods

open access: yes
In today's business environment, manufacturers need to manage their enterprises as an inseparable part of a supply chain. Key to achieving this is the creation of an extended and integrated information system.
Ivanova, Ivelina
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Gear ratio optimization of a full magnetic indirect drive chain for wind turbine applications

open access: yesInternational Conference on Ecological Vehicles and Renewable Energies, 2017
M. Desvaux   +5 more
semanticscholar   +1 more source

内置式力矩电机在数控滚齿机设计中的应用研究

open access: yesJixie chuandong, 2006
Based on introducing the concept and the basic character about zero-drive chain, workpiece axis of conventional mode and "zero-drive chain" mode in CNC gear hobbiong machine are compared in technology and in economy.
黄强, 张根保, 罗辑
doaj  

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

链条谐波传动中刚轮齿廓曲线方程的研究

open access: yesJixie chuandong, 2004
The harmonic drive is regarded as a great breakthrough of the mechanical drive. But the harmonic gear drive has some insurmountable defects. This paper introduces a new type of harmonic drive--the harmonic chain drive.
宋冠英, 陈树昌
doaj  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

齿形链传动在汽车变速箱及分动箱中的应用

open access: yesJixie chuandong, 2012
New silent chains with diverse structures and diverse meshing mechanisms are used in gearbox and transfer case for automobile gradually.On the basis of discussing the important technical characteristics of silent chain,the application advantages of ...
叶斌, 王洪军, 王丹
doaj  

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