Results 121 to 130 of about 309,624 (329)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Chain Drive Computional Model as Virtual Engine Module
, 2010 his work deals with the methods of creating computational models for the analysis of the chain drive of camshafts in combustion engines. Methods are compared of the simulation of the drive mechanism; a new method is also presented for the simulation of ...
Vlastník, Jan
core
Camshaft Drive Torque Measuring Device Built in a Chain Sprockt
, 2012 A device built in a camshaft drive chain sprocket for detecting precise torque fluctuation with minimum change on the valve drive system dynamical characteristics was developed. Strain gages are placed on thin plate areas in the sprocket disc. The signal
Masao Ishihama +2 more
core +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Drive chain friction characterization of a 6DOF parallel kinematics robot
, 2019 This paper describes a time-efficient method for friction characterization on a Robot drive chain, namely a Ball-screw transmission. The Method promotes practical application by being independent from external sensors and giving very precise and usable ...
Raineri I. +3 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
A Study on Finite Element Method of Sidebar of Oftset Drive China
Jixie chuandong, 1995 The offset dried chain is a kind of engineering steel chain which always works in rugged environments. It is important to analyze the mechanics properties of sidebar.
董华明, 王淑云, 王义行
doaj
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Chain conveyor drive for passenger transport
, 2018 Tato bakalářská práce pojednává o návrhu konstrukce pohonné jednotkyřetězového dopravníku pro dopravu osob, přesněji eskalátoru. V teoretické části jeblíže popsán princip mechanismu pohonu eskalátorů, jejich funkce, základníparametry a aktuální nabídka ...
Havlíček, Matěj
core
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source