Results 61 to 70 of about 4,250,637 (303)

Lorlatinib‐Containing Therapy for MYCN‐Amplified, ALK‐Mutated Neuroblastoma With Bulky Leptomeningeal Relapse: A Case Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Central nervous system (CNS) relapse of neuroblastoma carries a poor prognosis, and craniospinal irradiation (CSI) poses substantial long‐term toxicity in young children. We report a toddler with MYCN‐amplified neuroblastoma harboring somatic ALK R1275Q who developed extensive leptomeningeal relapse with paraplegia.
Jinwoo Kim, Minji Kim, Nani Jung, Sung Eun Kim, Ji Yoon Kim, Mi Ae Chu, Jung Eun Kwon, Yeo Hyang Kim, So Mi Lee, Ki‐Su Park, Jeong Eun Lee, Ye Jee Shim   +11 more
wiley   +1 more source

Driven Quantum Coarsening [PDF]

Physical Review Letters, 2009
We study the driven dynamics of quantum coarsening. We analyze models of M-component rotors coupled to two electronic reservoirs at different chemical potentials that generate a current threading through the system. In the large M limit we derive the dynamical phase diagram as a function of temperature, strength of quantum fluctuations, voltage and ...
Aron, Camille, Biroli, Giulio, Cugliandolo, Leticia   +2 more
openaire   +3 more sources

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

nbouziani/physics-driven-ml: v0.1.0

<h2>What's Changed</h2> <ul> <li>Add conftest.py by @nbouziani in https://github.com/nbouziani/physics-driven-ml/pull/4</li> <li>Update firedrake.ml import by @nbouziani in https://github.com/nbouziani/physics-driven ...
Nacime Bouziani
core   +1 more source

AI-powered segmentation and prognosis with missing MRI in pediatric brain tumors

npj Precision Oncology
Brain MRI is the primary imaging modality for pediatric brain tumors, yet incomplete acquisitions are common, hindering the clinical utility of existing deep learning models for tumor segmentation and prognosis.
Dimosthenis Chrysochoou, Deep B. Gandhi, Sahand Adib, Ariana M. Familiar, Bhavyasri Vunnava, Sanaz Varshochi, Neda Khalili, Nastaran Khalili, Jeffrey B. Ware, Wenxin Tu, Paarth Jain, Hannah Anderson, Shuvanjan Haldar, Phillip B. Storm, Andrea Franson, Michael Prados, Cassie Kline, Sabine Mueller, Adam Resnick, Arastoo Vossough, Christos Davatzikos, Ali Nabavizadeh, Anahita Fathi Kazerooni   +22 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Maturity of Software Modelling and Model Driven Engineering: a Survey in the Italian Industry [PDF]

, 2012
Background: The main claimed advantage of Model-driven engineering is improvement in productivity. However, few information is available about its actual adoption during software development and maintenance in the industry.
Tiso, Alessandro, Tomassetti, Federico Cesare Argentino, Gianna Reggio, Reggio, Gianna, F. Tomassetti, F. Ricca, Federico Tomassetti, G. Reggio, Alessandro Tiso, M. Torchiano, A. Tiso, Filippo Ricca, Ricca, Filippo, Torchiano, Marco, Marco Torchiano   +14 more
core   +1 more source

Transverse dose profile simulation of extruded lines for a 3D printed models for superficial skin cancer therapy

Current Directions in Biomedical Engineering, 2020
The short-range and sharp dose fall-off of beta particles in tissue make them an interesting option for use in the radiation therapy of superficial skin tumors.
Pashazadeh Ali, Friebe Michael
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Models, Modeling, and Model-Driven Development

, 2020
Models can be refined and finally be transformed into a technical implementation, i.e., a software system.
Brown, AW
core