Results 81 to 90 of about 4,023,817 (302)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

An interpretable machine learning model predicts the interactive and cumulative risks of different environmental chemical exposures on depression

open access: yesTranslational Psychiatry
Humans are exposed to a multitude of environmental chemical mixtures (ECMs) in daily life that may influence depression risk. While prior studies have shown individual ECM exposures to depression, the cumulative and interactive effects of multiple co ...
Gang Luo   +11 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

The Role of Dashboards in Augmented-Reality-Based Language Learning: Enhancing Language Learning and Metacognitive Awareness

open access: yesSAGE Open
The development of information and communication technologies has created limitless prospects for using augmented reality (AR) in various fields. Unfortunately, the multitasking nature of AR systems prevents learners from successfully reflecting and ...
Xuewang Geng, Masanori Yamada
doaj   +1 more source

The strength of bank-firm ties: how direct and indirect board connections affect debt financing

open access: yesBorsa Istanbul Review
This study examines how both direct and indirect links to banks, formed through board members' professional connections, affect a firm's access to debt financing.
Dmitry Kirpishchikov   +2 more
doaj   +1 more source

Meta-driven Browsers

open access: yes, 2007
Smalltalk is not only an object-oriented programming language; it is also known for its extensive integrated development environment supporting interactive and dynamic programming. While the default tools are adequate for browsing the code and developing applications, it is often cumbersome to extend the environment to support new language constructs ...
Alexandre Bergel   +3 more
openaire   +3 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Challenges Concerning Data-Driven Innovation [Elektronisk resurs]

open access: yes, 2017
Digital transformation is highly relevant to most organisations in the business and the government sectors. One important aspect of digital transformation is the capability to exploit data in order to develop new services.
Göbel, Hannes,   +2 more
core  

Ergodicity of hypoeliptic SDEs driven by fractional Brownian motion [PDF]

open access: yes, 2009
We demonstrate that stochastic differential equations (SDEs) driven by fractional Brownian motion with Hurst parameter H > 1/2 have similar ergodic properties as SDEs driven by standard Brownian motion.
Hairer, Martin, Pillai, Natesh S.
core  

The Eddy-Driven Thermocline

open access: yesJournal of Physical Oceanography, 2004
Abstract The role of baroclinic eddies in transferring thermal gradients laterally, and thus determining the stratification of the ocean, is examined. The hypothesis is that the density differences imposed at the surface by differential heating are a source of available potential energy that can be partially released by mesocale eddies ...
Cessi, P., M.Fantini
openaire   +4 more sources

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